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Eric Topol

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3037 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

This seems like a perfect way in the future that we could assure that a person's inflammatory state, and it doesn't have to be these proteins, it could be pretty much any protein, right?

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You could do that in real time.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Now, do you see a way where you could get this signal to your smartphone?

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Yeah.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

I mean, so for me, so into the new era of prevention that's been potentiated with these markers that you're adding a whole different level of sophistication of marker, I would say.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

And we don't have very good systemic blood markers now.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

We use high sensitivity CRP, maybe IL-6, but this is a whole different look being able to do this and

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

continuous in real time.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Now, other ways that this could be used are, you know, for trying to prevent Alzheimer's disease, autoimmune diseases.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

One of the ones that you posited was heart failure by, for example, continuous measurement of the BNP peptides, the

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

that tell us about the impending heart failure.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You may want to comment about this whole idea of using a sensor for protein monitoring for precision medicine.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You know, absolutely.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

There's unparalleled ways that this can go forward in both, as you say, research, but also in the management of and prevention of diseases.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

I mean, the autoimmune disease category is way up there in the list.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Now, how do you move forward?

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You've got this ingenious invention.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You've got a proof of it in the animal model.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

How do we accelerate this so that it becomes something that we could use in the clinic?

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Yeah, I mean, I've over the years tried to anticipate where things are going, and I haven't been as excited about