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Eric Topol

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3037 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

big dose, but rather chronic exposure.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

So maybe you could give us a bit of an overview of that review that you wrote for NEJM.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

Yeah.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

Yeah, it's pretty striking.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

The one that grabbed me, that kind of almost fell out of my chair, was that in 2019, I guess the most recent data, there is 5.5 million deaths, cardiovascular deaths, ascribed to relatively low levels, or I guess there is no safe level, of lead exposure.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

That's really striking.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

That's a lot of people dying from something that the cardiology and medical community is not really aware of.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

And there's a figure three that will also show in the text, the transcript, where you show the level where you start to see a takeoff.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

It starts very low.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

And by 50 micrograms per liter, you're seeing a twofold risk.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

And there's no threshold.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

It keeps going up.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

How many of us do you think are exposed to that type of level as adults, Bruce?

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

Yeah, but it looks like it's still a problem.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

And you have a phenomenal graph that's encouraging where you see this 95% reduction in lead exposure from the 1970s.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

And as you said, the factors that can be ascribed to like getting rid of lead from gasoline and others.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

But what is troubling is

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

is that we still have a lot of people that this could be a problem.

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

Now, one of the things that was fascinating is that you get into that herbal supplement,

Ground Truths
Bruce Lanphear: Chronic Lead Exposure, a Risk Factor for Heart Disease

could be a risk factor.