Erin Allman-Updike

This isn't necessarily happening in a superficial burn where it's just the epidermis.

Okay.

So just so I want to go over this, I think I make sure I understand this.

So you experience a second degree burn.

Let's say it's like on your leg.

There's the area that is like the most severe part that things are bad.

The burn has happened directly there.

And then-

surrounding that area there's sort of the the area that has also been kind of affected but not directly by the thermal injury but it's that area that needs to be like looked after because it's at risk of dying and so that's where a lot of the inflammation comes into their

Yes, yes.

But not necessarily the central point of the burn itself because there's nothing left.

There's no more tissue left to go to that is alive and receptive.

Right, right, right.

It has to do the remodeling first.

So yes, in that tissue that is completely dead, our inflammatory response can't kick in there.

We don't have blood flow there anymore.

There's no blood flow.

There's no opportunity for anything.

So then, okay, everything has to be restored.

Everything has to be restored.