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Ezra Klein

👤 Speaker
19393 total appearances
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The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

Eli Lilly also makes Zepound, the trisepatide variant.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

And this is in trials now, and it's expected that it will be approved in the next some amount of time, and it'll probably be a big deal.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

But

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

It works even better than the other two.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

But I don't really understand why all these people I know are getting a compounded thing from pharmacies they can't oversee when there are perfectly good GLP-1s on the market now that you could get and have full confidence in the way they're being manufactured.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

Like, what's going on with Reddit 2Tread?

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

Why is it both like around my community and all over my social media feeds?

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

No, this is just like straight up X for me.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

The argument I keep seeing about it is that it increases energy use, that it seems to have some independent effect on how much calories are burning.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

People I knew who used to order drugs on the Internet, they were ordering fun drugs.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

Now it's like these weird eat less and focus more.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

One thing I think is interesting about the GLP-1s, I mean, for everything we've talked about here, is, for instance, you know, the categories of who might want to lose a little bit of weight.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

or even more so, who might want to protect themselves from inflammation, they speak to this reality that the difference between well and sick is not this clear binary thing.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

We now have these categories like pre-diabetic and pre-hypertensive and pre-menopausal, and we didn't used to have them.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

I mean, we keep expanding the space in which you should worry.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

We have pre-overweight, pre-obese kind of things.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

And I think that there is an interesting dimension as people start looking for chemical answers to wellness.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

Because the truth is, for a lot of people, get enough sleep and go to the gym regularly and eat whole foods is hard.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

If you could give yourself a shot or take a pill, people want it.

The Ezra Klein Show
GLP-1s and the ‘Wild West’ of Wellness

And so how do you think about the broader shift, which is not new, but it's happening with more force right now, towards medicine as not a way of treating illness, but as a way of optimizing wellness?