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Freiburg

๐Ÿ‘ค Speaker
166 total appearances

Appearances Over Time

Podcast Appearances

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So what these guys did, which was really incredible, is they took stem cells, so stem cells that they got out of human blood, and they took those stem cells and they figured out a way to treat the stem cells so that those stem cells would start to make an excess amount of mitochondria than they normally would make.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So what these guys did, which was really incredible, is they took stem cells, so stem cells that they got out of human blood, and they took those stem cells and they figured out a way to treat the stem cells so that those stem cells would start to make an excess amount of mitochondria than they normally would make.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

In fact, they were able to get those stem cells to make 854 times the number of mitochondria that those cells would normally make. And those mitochondria were on average 5.7 times more efficient at making energy, ATP. So they created highly energetic mitochondria and they made a lot of them.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

In fact, they were able to get those stem cells to make 854 times the number of mitochondria that those cells would normally make. And those mitochondria were on average 5.7 times more efficient at making energy, ATP. So they created highly energetic mitochondria and they made a lot of them.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

And the idea that we can put mitochondria into our body or into tissue in our body to heal it or repair it has been something that folks have been trying to do research around for a long time. But the limiting factor is access to enough mitochondria.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

And the idea that we can put mitochondria into our body or into tissue in our body to heal it or repair it has been something that folks have been trying to do research around for a long time. But the limiting factor is access to enough mitochondria.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So this mechanism that they developed where they could take stem cells, make copies of the stem cells, make lots of mitochondria, and then they isolate that mitochondria and use it as a therapeutic tool. And they did it in cartilage that was damaged and they were able to heal that cartilage.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So this mechanism that they developed where they could take stem cells, make copies of the stem cells, make lots of mitochondria, and then they isolate that mitochondria and use it as a therapeutic tool. And they did it in cartilage that was damaged and they were able to heal that cartilage.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So this is a group that does bone and tissue repair studies, but they applied the mitochondria directly into the area where there was damage to the bone and the bone grew back and it actually improved the healing in an incredible way.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So this is a group that does bone and tissue repair studies, but they applied the mitochondria directly into the area where there was damage to the bone and the bone grew back and it actually improved the healing in an incredible way.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So this opens up the door to this whole new therapeutic modality, a new type of therapy called mitotherapy or mitochondrial therapy that based on the series of papers that we're seeing coming out recently, I believe could end up becoming a really incredible therapy new therapy that may ultimately lead to the treatment for many diseases that we're kind of dealing with right now.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So this opens up the door to this whole new therapeutic modality, a new type of therapy called mitotherapy or mitochondrial therapy that based on the series of papers that we're seeing coming out recently, I believe could end up becoming a really incredible therapy new therapy that may ultimately lead to the treatment for many diseases that we're kind of dealing with right now.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So I just wanted to kind of link those out.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

So I just wanted to kind of link those out.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

Yeah, I mean, what they did this in, and I think this was published in a research magazine called Bone or something, Bone and Tissue or something.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

Yeah, I mean, what they did this in, and I think this was published in a research magazine called Bone or something, Bone and Tissue or something.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

They did it in a model, a mouse model of osteoarthritis, and it repaired this osteoarthritis, but that's exactly right. And so that's tissue where you can, using a microscope, you can actually see the healing happening.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

They did it in a model, a mouse model of osteoarthritis, and it repaired this osteoarthritis, but that's exactly right. And so that's tissue where you can, using a microscope, you can actually see the healing happening.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

But you can see this being applied, for example, to cerebrospinal fluid, where you can basically increase the mitochondrial, the energetic mitochondrial production that finds its way into maybe neuronal cells, into neurons in your brain, and improves your brain function. Or you could put it into damaged hearts after heart attacks and improve heart function.

All-In with Chamath, Jason, Sacks & Friedberg
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon

But you can see this being applied, for example, to cerebrospinal fluid, where you can basically increase the mitochondrial, the energetic mitochondrial production that finds its way into maybe neuronal cells, into neurons in your brain, and improves your brain function. Or you could put it into damaged hearts after heart attacks and improve heart function.