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George Church

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
710 total appearances

Appearances Over Time

Podcast Appearances

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

We should make a biolat.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

It should be a small...

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

challenge goal for the synthetic biology community, maybe iGEM or something, make, you know, bacteria make a radio.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Now, actually, Joe Davis is an artist that's been affiliated with my lab and before that, Alex Rich's lab.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And he did make a bacterial radio, but it was kind of more on the art end than on the science end.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

But I think that would be a good goal.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So part of this has to do with just learning the rules of developmental biology, like I said.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

We can determine morphology at sort of the molecular level now, proteins, nucleic acids.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Determining at the cellular, multicellular level, there's a lot more things you can do and a lot faster.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

but we don't know the language yet.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

I think we're on the cusp of getting the tools to do that, like the transcription factor I was talking about earlier, harnessing, migration, gradients of factor, diffusion factors, chemotaxis and so forth.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So that's one thing we need, but there's a bunch of things we need, really.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Oh, I see what you're getting at.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So astronomy might be we would detect radio signals or light signals.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

But biology, the kind of evidence would be that you show in a laboratory using...

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

prebiotic conditions a really simple way to get life, right?

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Or, I mean, it's a harder proof to prove that given, because we don't know what all the possible prebiotic conditions, and probably the number was vast.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

I mean, you have 10 to the 20th liters of water and, you know,

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

at various different salinities and drying up on the ocean and the sun and the lightning and all this stuff.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

But yes, I think if you showed kind of reconstructed in the lab a very simple pathway from inorganics, cyanide derivatives and reduced compounds all the way up to, you know, some cellular replicating structure, I think that might...