Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Blog Pricing

George Church

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
710 total appearances

Appearances Over Time

Podcast Appearances

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

uh even in technological society so in technology you can you can jump to things that where all the intermediates aren't you know incrementally useful with evolution is as far as we know generally limited to you have to justify uh every change uh it's like some bureaucracy says well if you're gonna you put this sidewalk in you know you have to justify that before you can build a city

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

It's hard to say because as soon as you say it, it becomes hyped.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

If I've ever been asked this question before, it's too late.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

I would say

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

One thing I think is very ripe and is very well understood in a certain sense, but is nevertheless ignored.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

It's kind of like the previous example I would have chosen was making genes out of arrays.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Arrays were typically used for analytic, you know, quantitating RNAs or something like that.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So the original aphometrics type arrays.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

But we turned them into gene arrays.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And just...

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

people weren't using it.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

It was in nature, it was hidden in plain sight.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

But anyway, it was somehow underhyped.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

What I would say is genetic counseling is underhyped.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

It is clearly competitive with gene therapy in a certain sense.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

I mean, clearly not for people that are already born, but for people in the future, not even distant future, next couple of years.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

We've got a chance of diagnosing them or...

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

diagnosing the potential parents and dodging.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And this has been in practice since 1985 in Dorya Sharim.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Perfectly reasonable community response to it, eliminated or greatly reduced all sorts of very, very serious inherited diseases.