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George Church

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
710 total appearances

Appearances Over Time

Podcast Appearances

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And it's just...

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

don't need to uh we need to be careful not to stigmatize as well so when uh if a bunch of families get fixed we shouldn't point a finger at the ones that are unwilling to get fixed because that's their choice you know but i think as as word spreads and you see the positive outcomes i think that will be uh

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

It will be seen as one of the simplest bits of medicine ever.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

I mean, it's โ€“ in fact, it's something โ€“

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

hundred dollars per genome, and it'll probably be less soon, and you get the whole thing analyzed.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And, you know, compare that to millions of dollars that, you know, that will be lost, opportunity costs, them not being part of the workforce, the taking care of them and so forth.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So the return on investment is tremendous.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

It's at least a tenfold return on investment.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So it's a no-brainer from a public health standpoint.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

We should be able to pay for this through national health services in England, through insurance companies in the United States.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And it turns the insurance companies from being the bad guys, that they're snooping in on your personal life and then raising your rates, to, oh, they're giving you this free information and you can do with it as you wish.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And you could, if you...

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

take the advice, then you save them millions of dollars.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Absolutely.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

I've actually counseled my gene therapy companies that

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

that they should be investing in very common diseases, because rare diseases have this genetic counseling solution, with the exception of spontaneous mutations and dominance, which probably are IVF clinic-type solutions, but the rare recessives can be handled in matchmaking at every level.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Anyway, I counseled my genetic therapy companies that they should, you know, invest in common diseases like age-related diseases and infectious diseases.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And in fact, you know, the COVID vaccine was formulated as a gene therapy and was, you know, the cost was in the, you know, $20 per dose range and 6 billion people benefited from it.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Or 6 billion people took it and

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

and it was proven over the whole population.