Hamilton Morris
👤 PersonAppearances Over Time
Podcast Appearances
broadly represented I mean the alchemists were very very interested in urine without question the element phosphorus was discovered in urine from urine analysis I think the ancient Romans were drinking piss in some of their initiations I don't know about that but it seems possible I mean but the idea there is that yeah there's clearly some kind of transformation of foods that's occurring one issue is that
um many not all but many metabolic changes are oxidative in their character and increase the polarity of a drug in order to facilitate its excretion in urine this is kind of like if you were to There's a lot of things that can happen in the body. But if you were to broadly talk about what like phase one metabolism is, it often involves oxidation that increases polarity of a drug.
um many not all but many metabolic changes are oxidative in their character and increase the polarity of a drug in order to facilitate its excretion in urine this is kind of like if you were to There's a lot of things that can happen in the body. But if you were to broadly talk about what like phase one metabolism is, it often involves oxidation that increases polarity of a drug.
um many not all but many metabolic changes are oxidative in their character and increase the polarity of a drug in order to facilitate its excretion in urine this is kind of like if you were to There's a lot of things that can happen in the body. But if you were to broadly talk about what like phase one metabolism is, it often involves oxidation that increases polarity of a drug.
And one problem with that in terms of harnessing it for drug manufacturing is that the reason the body does this is specifically because it facilitates excretion and typically but not always deactivates a drug. So this is this is like our evolved process for reducing the activity of drugs. There are active metabolites.
And one problem with that in terms of harnessing it for drug manufacturing is that the reason the body does this is specifically because it facilitates excretion and typically but not always deactivates a drug. So this is this is like our evolved process for reducing the activity of drugs. There are active metabolites.
And one problem with that in terms of harnessing it for drug manufacturing is that the reason the body does this is specifically because it facilitates excretion and typically but not always deactivates a drug. So this is this is like our evolved process for reducing the activity of drugs. There are active metabolites.
There are instances of drugs that become more active through biotransformation, but they're often intentionally engineered that way. Not always.
There are instances of drugs that become more active through biotransformation, but they're often intentionally engineered that way. Not always.
There are instances of drugs that become more active through biotransformation, but they're often intentionally engineered that way. Not always.
There certainly could be. I mean, yeah, without question.
There certainly could be. I mean, yeah, without question.
There certainly could be. I mean, yeah, without question.
I mean, look at the ingredients in most products today. They have an insane number of different things that are each intended to alter the activity in its own little way, changing the taste, changing the color, modifying the pharmacology in various ways. We do that all the time.
I mean, look at the ingredients in most products today. They have an insane number of different things that are each intended to alter the activity in its own little way, changing the taste, changing the color, modifying the pharmacology in various ways. We do that all the time.
I mean, look at the ingredients in most products today. They have an insane number of different things that are each intended to alter the activity in its own little way, changing the taste, changing the color, modifying the pharmacology in various ways. We do that all the time.
So I see no reason that people wouldn't be aware of the, at the very least additive, if not synergistic effects that come from the,
So I see no reason that people wouldn't be aware of the, at the very least additive, if not synergistic effects that come from the,
So I see no reason that people wouldn't be aware of the, at the very least additive, if not synergistic effects that come from the,
But I'm not the person for the – especially when it comes to these very broad discussions. Like I could investigate the influence of a specific plant or a specific thing. But most of the practices that he was describing were so complicated that they don't really lend themselves to any kind of casual critical analysis. It's not the kind of thing –