Jonquilyn Hill

Yeah.

So it sounds like it's not even like sadness.

It's just sort of nothing.

Nothing.

Yeah, like the same excitement you might get from like, oh, I'm going to eat this pizza later.

You're also not getting this, oh, I'm going to see my friend later.

Or, oh, I can't wait to go to this concert.

You know, you're kind of dampening this anticipatory response, right?

So one of the theories in the literature is that it's not just

changing your appetite and metabolism, right?

Because think about it.

If it's also helping gambling and shopping addictions, that can't be just about metabolism.

Pharmacological activation of GLP-1 receptors appears to reduce alcohol intake in preclinical models and early human studies, possibly by dampening reward signaling in the brain.

So how are we making sense of this?

That it is helping with people not being as motivated to eat as much.

They're not getting that food noise, but they're also not gambling and shopping.

And of course, we look at all three of those as kind of negative, but what kind of positives might that be dulling?

What I find interesting is that people are starting to come out of the woodwork and kind of noticing that, right?

I'm definitely feeling this like flat, like...

just kind of like blah feeling.