Kevin McKernan
๐ค SpeakerAppearances Over Time
Podcast Appearances
We etched some things into Bitcoin as well on this. We put them on IPFS and then we put the extra time to make protocols. that you could question this with something really cheap like PCR. If someone had to go and sequence vaccines, that could cost more money and take more time.
But if you take the extra effort to make it easy for someone to check your work, like build a PCR assay that someone can do in an afternoon for a couple hundred bucks, then others pick it up. And we got that with, um, Philip Buchholz. He, he reproduced it. God is, you know, he got all types of hell for doing it. Um, and then, um, yeah, who is he again? He's a professor.
But if you take the extra effort to make it easy for someone to check your work, like build a PCR assay that someone can do in an afternoon for a couple hundred bucks, then others pick it up. And we got that with, um, Philip Buchholz. He, he reproduced it. God is, you know, he got all types of hell for doing it. Um, and then, um, yeah, who is he again? He's a professor.
But if you take the extra effort to make it easy for someone to check your work, like build a PCR assay that someone can do in an afternoon for a couple hundred bucks, then others pick it up. And we got that with, um, Philip Buchholz. He, he reproduced it. God is, you know, he got all types of hell for doing it. Um, and then, um, yeah, who is he again? He's a professor.
He's a cancer biologist down in, um, University of South Carolina, and has an incredible background, came out of Bert Vogelstein's lab at JHU. JHU and Bert's lab are, you know, they're the top cancer docs in the world, right? Everyone who comes out of there, they have just very inventive minds.
He's a cancer biologist down in, um, University of South Carolina, and has an incredible background, came out of Bert Vogelstein's lab at JHU. JHU and Bert's lab are, you know, they're the top cancer docs in the world, right? Everyone who comes out of there, they have just very inventive minds.
He's a cancer biologist down in, um, University of South Carolina, and has an incredible background, came out of Bert Vogelstein's lab at JHU. JHU and Bert's lab are, you know, they're the top cancer docs in the world, right? Everyone who comes out of there, they have just very inventive minds.
Actually, our sequencer that we built, the solid sequencer, we licensed stuff out of Bert's lab because they invented emulsion PCR, and it was a very handy technique. Okay. But Philip came out of there, and he saw this. I was posting this on Twitter, and he was like, well, I don't know. This guy looks like he knows genomics.
Actually, our sequencer that we built, the solid sequencer, we licensed stuff out of Bert's lab because they invented emulsion PCR, and it was a very handy technique. Okay. But Philip came out of there, and he saw this. I was posting this on Twitter, and he was like, well, I don't know. This guy looks like he knows genomics.
Actually, our sequencer that we built, the solid sequencer, we licensed stuff out of Bert's lab because they invented emulsion PCR, and it was a very handy technique. Okay. But Philip came out of there, and he saw this. I was posting this on Twitter, and he was like, well, I don't know. This guy looks like he knows genomics.
He's got a history, but this is all kind of โ I'm going to fact check this guy. And he ordered the primers that I put up on our website, ran it, and was like, holy shit, this works. So then he went about and designed his own primers to make sure he wasn't like โ I wasn't feeding him some trick. And those worked.
He's got a history, but this is all kind of โ I'm going to fact check this guy. And he ordered the primers that I put up on our website, ran it, and was like, holy shit, this works. So then he went about and designed his own primers to make sure he wasn't like โ I wasn't feeding him some trick. And those worked.
He's got a history, but this is all kind of โ I'm going to fact check this guy. And he ordered the primers that I put up on our website, ran it, and was like, holy shit, this works. So then he went about and designed his own primers to make sure he wasn't like โ I wasn't feeding him some trick. And those worked.
And then he went and sequenced it with Oxford nanopore and he got the whole plasmid and was like, yeah, this is a problem. We have a lot of this DNA there and it's in an LNP and that's very different. The regulations they have for 10 nanograms are irrelevant. We have to. We've got to start scanning tumors now and see if this has played a role.
And then he went and sequenced it with Oxford nanopore and he got the whole plasmid and was like, yeah, this is a problem. We have a lot of this DNA there and it's in an LNP and that's very different. The regulations they have for 10 nanograms are irrelevant. We have to. We've got to start scanning tumors now and see if this has played a role.
And then he went and sequenced it with Oxford nanopore and he got the whole plasmid and was like, yeah, this is a problem. We have a lot of this DNA there and it's in an LNP and that's very different. The regulations they have for 10 nanograms are irrelevant. We have to. We've got to start scanning tumors now and see if this has played a role.
He's a bit more conservative on it, and I don't blame him based on the role that he's in. He doesn't want to raise alarm bells. He doesn't want to spread panic. He's also in an academic setting where deans kind of come down on you if you do that.
He's a bit more conservative on it, and I don't blame him based on the role that he's in. He doesn't want to raise alarm bells. He doesn't want to spread panic. He's also in an academic setting where deans kind of come down on you if you do that.
He's a bit more conservative on it, and I don't blame him based on the role that he's in. He doesn't want to raise alarm bells. He doesn't want to spread panic. He's also in an academic setting where deans kind of come down on you if you do that.
But it's good to have someone like him with a different perspective that's more cautious about this because that can be sobering for when you're alone in a field like this. There's another group in Germany that reproduced it as well, and they actually got it through peer review, Bridget Koenig's group, which I was shocked by that they managed to push it through.