Lee Cronin

It is. It becomes harder. But one of the things that's super nice is that it constrains your initial conditions, right? Sure. It constrains where you're going to be. So if you take, say, imagine... So one of the things we're doing right now is applying assembly theory to drug discovery. Mm-hmm.

It is. It becomes harder. But one of the things that's super nice is that it constrains your initial conditions, right? Sure. It constrains where you're going to be. So if you take, say, imagine... So one of the things we're doing right now is applying assembly theory to drug discovery. Mm-hmm.

Now, what everyone's doing right now is taking all the proteins and looking at the proteins and looking at molecules docked with proteins. Why not instead look at the molecules that are involved in interacting with the receptors over time, rather than thinking about and use the molecules that evolve over time as a proxy for how the proteins evolved over time?

Now, what everyone's doing right now is taking all the proteins and looking at the proteins and looking at molecules docked with proteins. Why not instead look at the molecules that are involved in interacting with the receptors over time, rather than thinking about and use the molecules that evolve over time as a proxy for how the proteins evolved over time?

Now, what everyone's doing right now is taking all the proteins and looking at the proteins and looking at molecules docked with proteins. Why not instead look at the molecules that are involved in interacting with the receptors over time, rather than thinking about and use the molecules that evolve over time as a proxy for how the proteins evolved over time?

Mm-hmm.

Mm-hmm.

Mm-hmm.

and then use that to constrain your drug discovery process. You flip the problem 180 and focus on the molecule evolution rather than the protein. And so you can guess in the future what might happen. So rather than having to consider all possible molecules, you know where to focus.

and then use that to constrain your drug discovery process. You flip the problem 180 and focus on the molecule evolution rather than the protein. And so you can guess in the future what might happen. So rather than having to consider all possible molecules, you know where to focus.

and then use that to constrain your drug discovery process. You flip the problem 180 and focus on the molecule evolution rather than the protein. And so you can guess in the future what might happen. So rather than having to consider all possible molecules, you know where to focus.

And that's the same thing if you're looking in assembly spaces for an object where you don't know the entire history, but you know that in the history of this object, it's not going to have some other motif there that doesn't appear in the past.

And that's the same thing if you're looking in assembly spaces for an object where you don't know the entire history, but you know that in the history of this object, it's not going to have some other motif there that doesn't appear in the past.

And that's the same thing if you're looking in assembly spaces for an object where you don't know the entire history, but you know that in the history of this object, it's not going to have some other motif there that doesn't appear in the past.

No.

No.

No.

Well, this is another thing that I think causes, because this paper goes across so many boundaries. So chemists have looked at this and said, this is not a correct reaction. It's like, no, it's a graph.

Well, this is another thing that I think causes, because this paper goes across so many boundaries. So chemists have looked at this and said, this is not a correct reaction. It's like, no, it's a graph.

Well, this is another thing that I think causes, because this paper goes across so many boundaries. So chemists have looked at this and said, this is not a correct reaction. It's like, no, it's a graph.