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Lee Cronin

๐Ÿ‘ค Speaker
1635 total appearances

Appearances Over Time

Podcast Appearances

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

yeah and so and what you do is you look at the minimal constraints on that graph of course it has some mapping to the synthesis but actually you don't have to know all of chemistry you just have to understand you can build up the constraint space rather nicely um but this is just at the beginning right there are so many directions this could go in and i said it it could all be wrong but hopefully it's less wrong what about the little criticism i saw of do you uh

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

yeah and so and what you do is you look at the minimal constraints on that graph of course it has some mapping to the synthesis but actually you don't have to know all of chemistry you just have to understand you can build up the constraint space rather nicely um but this is just at the beginning right there are so many directions this could go in and i said it it could all be wrong but hopefully it's less wrong what about the little criticism i saw of do you uh

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

yeah and so and what you do is you look at the minimal constraints on that graph of course it has some mapping to the synthesis but actually you don't have to know all of chemistry you just have to understand you can build up the constraint space rather nicely um but this is just at the beginning right there are so many directions this could go in and i said it it could all be wrong but hopefully it's less wrong what about the little criticism i saw of do you uh

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

No, no. Well, let's go back. So no, not less likely, but react. So no. So let's go back to what we're looking at here. So the assembly index is the minimal path. Mm-hmm. that could have created that object probabilistically. So imagine you have all your atoms in a plasma, you've got enough energy, you've got enough collisions.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

No, no. Well, let's go back. So no, not less likely, but react. So no. So let's go back to what we're looking at here. So the assembly index is the minimal path. Mm-hmm. that could have created that object probabilistically. So imagine you have all your atoms in a plasma, you've got enough energy, you've got enough collisions.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

No, no. Well, let's go back. So no, not less likely, but react. So no. So let's go back to what we're looking at here. So the assembly index is the minimal path. Mm-hmm. that could have created that object probabilistically. So imagine you have all your atoms in a plasma, you've got enough energy, you've got enough collisions.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

What is the quickest way you could zip out that molecule with no reaction constraints?

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

What is the quickest way you could zip out that molecule with no reaction constraints?

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

What is the quickest way you could zip out that molecule with no reaction constraints?

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

It's just basically a walk on a random graph. So we make an assumption that basically the timescale for forming the bonds. So no, I don't want to say that because it's going to have people getting obsessing about this point. And your criticism is a really good one. What we're trying to say is like, this puts a lower bound on something. Of course, some reactions are less possible than others.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

It's just basically a walk on a random graph. So we make an assumption that basically the timescale for forming the bonds. So no, I don't want to say that because it's going to have people getting obsessing about this point. And your criticism is a really good one. What we're trying to say is like, this puts a lower bound on something. Of course, some reactions are less possible than others.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

It's just basically a walk on a random graph. So we make an assumption that basically the timescale for forming the bonds. So no, I don't want to say that because it's going to have people getting obsessing about this point. And your criticism is a really good one. What we're trying to say is like, this puts a lower bound on something. Of course, some reactions are less possible than others.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

But actually, I don't think chemical reactions exist. Oh boy. What does that mean? Why don't chemical reactions exist? I'm writing a paper right now that I keep being told I have to finish. And it's called The Origin of Chemical Reactions. And it merely says that reactivity exists as controlled by the laws of quantum mechanics. And reactions, chemists put names on reactions.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

But actually, I don't think chemical reactions exist. Oh boy. What does that mean? Why don't chemical reactions exist? I'm writing a paper right now that I keep being told I have to finish. And it's called The Origin of Chemical Reactions. And it merely says that reactivity exists as controlled by the laws of quantum mechanics. And reactions, chemists put names on reactions.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

But actually, I don't think chemical reactions exist. Oh boy. What does that mean? Why don't chemical reactions exist? I'm writing a paper right now that I keep being told I have to finish. And it's called The Origin of Chemical Reactions. And it merely says that reactivity exists as controlled by the laws of quantum mechanics. And reactions, chemists put names on reactions.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

So you could have like, I don't know, the Wittig reaction, which is by Wittig. You could have the Suzuki reaction, which is by Suzuki. Mm-hmm. Now, what are these reactions? So these reactions are constrained by the following. They're constrained by the fact they're on planet Earth, 1G, 298 Kelvin, one bar. So these are constraints. They're also constrained by the chemical composition of Earth.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

So you could have like, I don't know, the Wittig reaction, which is by Wittig. You could have the Suzuki reaction, which is by Suzuki. Mm-hmm. Now, what are these reactions? So these reactions are constrained by the following. They're constrained by the fact they're on planet Earth, 1G, 298 Kelvin, one bar. So these are constraints. They're also constrained by the chemical composition of Earth.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

So you could have like, I don't know, the Wittig reaction, which is by Wittig. You could have the Suzuki reaction, which is by Suzuki. Mm-hmm. Now, what are these reactions? So these reactions are constrained by the following. They're constrained by the fact they're on planet Earth, 1G, 298 Kelvin, one bar. So these are constraints. They're also constrained by the chemical composition of Earth.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

Oxygen, availability, all this stuff. And that then allows us to focus in our chemistry. So when a chemist does a reaction, that's a really nice compressed shorthand for constraint application. Glass flask.

Lex Fridman Podcast
#404 โ€“ Lee Cronin: Controversial Nature Paper on Evolution of Life and Universe

Oxygen, availability, all this stuff. And that then allows us to focus in our chemistry. So when a chemist does a reaction, that's a really nice compressed shorthand for constraint application. Glass flask.