Louisa Nicola
👤 PersonAppearances Over Time
Podcast Appearances
It is super scary. So you're right. 55 million people worldwide have Alzheimer's disease. That number will triple by the year 2050. And it seems to be a cascade of different factors that affect it. It's my sole understanding that it comes down to three factors. The first one being... inactivity, so lack of exercise, lack of adequate sleep, and then lack of proper nutrition.
It is super scary. So you're right. 55 million people worldwide have Alzheimer's disease. That number will triple by the year 2050. And it seems to be a cascade of different factors that affect it. It's my sole understanding that it comes down to three factors. The first one being... inactivity, so lack of exercise, lack of adequate sleep, and then lack of proper nutrition.
It is super scary. So you're right. 55 million people worldwide have Alzheimer's disease. That number will triple by the year 2050. And it seems to be a cascade of different factors that affect it. It's my sole understanding that it comes down to three factors. The first one being... inactivity, so lack of exercise, lack of adequate sleep, and then lack of proper nutrition.
Yeah.
Yeah.
Yeah.
Well, we have to understand, first of all, the pathophysiology of Alzheimer's disease. So we know in these neurodegenerative diseases, neurodegenerative, so they build up over time. More often than not, you're getting diagnosed with your first symptom of Alzheimer's disease around 65 years old. And the first sign is episodic memory. That is the first thing that starts to go.
Well, we have to understand, first of all, the pathophysiology of Alzheimer's disease. So we know in these neurodegenerative diseases, neurodegenerative, so they build up over time. More often than not, you're getting diagnosed with your first symptom of Alzheimer's disease around 65 years old. And the first sign is episodic memory. That is the first thing that starts to go.
Well, we have to understand, first of all, the pathophysiology of Alzheimer's disease. So we know in these neurodegenerative diseases, neurodegenerative, so they build up over time. More often than not, you're getting diagnosed with your first symptom of Alzheimer's disease around 65 years old. And the first sign is episodic memory. That is the first thing that starts to go.
What you did that day, somebody's name, somebody that you met, you know, that short-term memory, that's the first thing to go. And then you actually get diagnosed at about 70 years old with the disease. And this is an accumulation of amyloid beta, which is a protein. I'm not going to call it a toxic protein.
What you did that day, somebody's name, somebody that you met, you know, that short-term memory, that's the first thing to go. And then you actually get diagnosed at about 70 years old with the disease. And this is an accumulation of amyloid beta, which is a protein. I'm not going to call it a toxic protein.
What you did that day, somebody's name, somebody that you met, you know, that short-term memory, that's the first thing to go. And then you actually get diagnosed at about 70 years old with the disease. And this is an accumulation of amyloid beta, which is a protein. I'm not going to call it a toxic protein.
I'm just going to call it a protein in the brain that we all have that aggregates, it clumps together over time, and it eventually leads to neuron cell death. So this is a long progression. It starts around 25 years old, 30 years old. So the things that we're doing from our 30s impact how our brain will survive at age 70 onwards. Sleep is so fundamentally important for many reasons.
I'm just going to call it a protein in the brain that we all have that aggregates, it clumps together over time, and it eventually leads to neuron cell death. So this is a long progression. It starts around 25 years old, 30 years old. So the things that we're doing from our 30s impact how our brain will survive at age 70 onwards. Sleep is so fundamentally important for many reasons.
I'm just going to call it a protein in the brain that we all have that aggregates, it clumps together over time, and it eventually leads to neuron cell death. So this is a long progression. It starts around 25 years old, 30 years old. So the things that we're doing from our 30s impact how our brain will survive at age 70 onwards. Sleep is so fundamentally important for many reasons.
One is, and we'll talk about the different sleep stages, but sleep is where you can repair your brain. You have to think of your brain. It is an organ, but it's also like a muscle fundamentally. We need to rest our body, right? In order for our muscles to grow, regenerate, we need to rest them. We need to hydrate them. We need to fuel them. That's what sleep does for your brain.
One is, and we'll talk about the different sleep stages, but sleep is where you can repair your brain. You have to think of your brain. It is an organ, but it's also like a muscle fundamentally. We need to rest our body, right? In order for our muscles to grow, regenerate, we need to rest them. We need to hydrate them. We need to fuel them. That's what sleep does for your brain.
One is, and we'll talk about the different sleep stages, but sleep is where you can repair your brain. You have to think of your brain. It is an organ, but it's also like a muscle fundamentally. We need to rest our body, right? In order for our muscles to grow, regenerate, we need to rest them. We need to hydrate them. We need to fuel them. That's what sleep does for your brain.
And sadly, we're going through an epidemic of sleep deprivation, which is classified as six hours or less. Now, I live in New York. You probably look around you. Most people are sleeping around six hours or less. That's just due to the busy city life. But during sleep, we go through different stages. And the most important stages are deep, slow-wave sleep, which is your stage three sleep.
And sadly, we're going through an epidemic of sleep deprivation, which is classified as six hours or less. Now, I live in New York. You probably look around you. Most people are sleeping around six hours or less. That's just due to the busy city life. But during sleep, we go through different stages. And the most important stages are deep, slow-wave sleep, which is your stage three sleep.