Menu
Sign In Search Podcasts Libraries Charts People & Topics Add Podcast API Blog Pricing

Luke O'Neill

👤 Speaker
1510 total appearances

Appearances Over Time

Podcast Appearances

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

What have they done there?

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Well, again, that's a nasty one, Pat.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

If you're diagnosed with that, it's usually too late and you're literally given months to live at the more extreme end of it.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

And this is quite surprising.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Well, first of all, a drug that's used for something else, for Cushing's disease.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Now, this is a disease where you make too much cortisol.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

They noticed if you're on that drug for Cushing's disease, it seemed to work in ovarian as well.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

It's called Relacortisant is the name of the drug.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

And especially for those who resist other therapies.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

So normally you get these platinum-based chemo drugs and they don't work in ovarian.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

You give them this drug and lo and behold, again, they extended life.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

There was a 36% reduction of death in this phase, which is great to see.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Now, it's still quite small.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

It's a four-month extension of life at the moment.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

But even still, that's a few months that are added to people's lives.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

And again, they're thinking, if we can optimise that now and get it even better, it'll be really wonderful.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

And that was unusual because it's a drug that's widely used.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

It's a strange thing, you know.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

So, obviously, they know it's side effects and safety.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Yeah, freely available.