Mark Zuckerberg

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5,808 appearances 84 recordings 48 series first heard Jun 2023 last heard yesterday

Mark Zuckerberg’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 32 in all, peaking in Jan 2026 with 6.

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The a16z Show · Mark Zuckerberg & Priscilla Chan: How AI Will Help Cure Disease · 9 Jul 2026 podcast

And then you can test against that.

The cryo model, I think, is interesting because it's spatial.

So it kind of gives you a sense of there are all these different models that you can have that allow you to basically look at different kinds of things.

Then you just train them in to be increasingly general over time.

Oh, that's actually a fascinating one, too.

Because one of the new models, I think this one is very early, but it's basically the first reasoning model over biology.

So the idea is that...

Yeah, you effectively have these models that kind of simulate world models in different ways.

And then you want it to be able to not just be able to spit out correlations, right, in terms of like what it's found, but actually be able to kind of reason through how things would evolve and why things would happen.

Right.

I know it's quite early, but it is interesting conceptually as what I think is clearly going to be an important direction in terms of how these models evolve.

Well, yeah, sure, sure.

Yeah, I mean, the...

I thought you were saying if the reasoning model doesn't work, why?

I mean, the language model analogy for that would be you need better kind of world models or better pre-trained models in order to get the reasoning to be good.

But yeah, you build more

You build more capabilities into it.

And I think that there's probably an order too.

So the work that Alex and the evolutionary scale folks worked on is a lot of it is protein, which is interesting because that's at a kind of smaller resolution, obviously, than the cellular data and the cell outlets.

But part of the hypothesis is that

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