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Michael Levin

๐Ÿ‘ค Speaker
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4080 total appearances
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Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

Yeah.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So here's what we've done, right?

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So we've more or less solved that in frogs.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So frogs, unlike salamanders, do not regenerate their legs as adults.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

And so we've shown that with a very kind of simple intervention.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So what we do is there's two things.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

You need to have a signal that tells the cells what to do, and then you need some way of delivering it.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

And so this is work together with David Kaplan, and I should do a disclosure here.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

We have a company called Morphoceuticals and a spinoff.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

where we're trying to address limb regeneration.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So we've solved it in the frog and we're now in trials in mice.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So now we're going to order in mammals now.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

I can't say anything about how it's going, but the frog thing is solved.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

Yeah, basically.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

Basically, yeah.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

Yeah.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So what you do is we did we did with legs instead of forearms.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

And what you do is after amputation, normally they don't regenerate.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

You put on a wearable bioreactor.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So it's this thing that that goes on.