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Michael Levin

๐Ÿ‘ค Speaker
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4080 total appearances
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Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

And Dave Kaplan's lab makes these things.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

And inside it's a it's a very controlled environment.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

It is a silk gel that carries some drugs, for example, ion channel drugs.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

And what you're doing is you're saying to these cells.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

You should regrow what normally goes here.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So that whole thing is on for 24 hours.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

Then you take it off.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

You don't touch the leg again.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

This is really important because what we're not looking for is a set of micromanagement, you know, printing or controlling the cells.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

We want to trigger.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

We want to interact with it early on and then not touch it again because we don't know how to make a frog leg.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

But the frog knows how to make a frog leg.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So 24 hours.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

18 months of leg growth after that without us touching it again and after 18 months you get a pretty good leg that kind of shows this proof of concept that early on when the cells right after injury when they're first making a decision about what they're going to do you can you can impact them and once they've decided to make a leg they don't need you after that they can you know do their own thing so that's an approach that we're now taking what about cancer suppression that's something you mentioned earlier how can all of these ideas help with cancer suppression

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So let's go back to the beginning and ask what cancer is.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So I think, you know, asking why there's cancer is the wrong question.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

I think the right question is why is there ever anything but cancer?

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

So in the normal state, you have a bunch of cells that are all cooperating towards a large scale goal.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

If that process of cooperation breaks down and you've got a cell that is isolated from that electrical network that lets you remember what the big goal is, you revert back to your unicellular lifestyle.

Lex Fridman Podcast
#325 โ€“ Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

Now, think about that border between self and world, right?