Mike Israetel

Primobolin is a synthetic anabolic androgenic steroid developed in, I think, the 60s and 70s. And it's designed not really to convert into estrogen hardly at all. Other steroids like it are master on. They not only don't convert into estrogen, but they actually antagonize estrogen conversion for the testosterone you're shooting in to some extent.

And so if someone's like way too much estrogen for them, they can do a 50-50 split of testosterone and primobolin. so that now they get all the good estrogen from testosterone, but not too much of it, but they get most of that anabolic drive from the rest of the primobolin, but without any more estrogen addition. It could be 250 testosterone and 750 milligrams of primo. It can be 750 test.

And so if someone's like way too much estrogen for them, they can do a 50-50 split of testosterone and primobolin. so that now they get all the good estrogen from testosterone, but not too much of it, but they get most of that anabolic drive from the rest of the primobolin, but without any more estrogen addition. It could be 250 testosterone and 750 milligrams of primo. It can be 750 test.

It can be 250 primo and anything between. And you kind of experiment that in a lot of bodybuilding coaches.

It can be 250 primo and anything between. And you kind of experiment that in a lot of bodybuilding coaches.

What they're really good at is starting you on a certain cycle that they have the wisdom to know works for most people, and then leveling up one drug, leveling down another to get, among other things, kind of that testosterone, that androgen to estrogen ratio to be something that you have your best performance at, best health, so on and so forth.

What they're really good at is starting you on a certain cycle that they have the wisdom to know works for most people, and then leveling up one drug, leveling down another to get, among other things, kind of that testosterone, that androgen to estrogen ratio to be something that you have your best performance at, best health, so on and so forth.

But the sex drive component, especially if you have a lot of estrogen going on, qualitatively it can change, quantitatively it can change. Now, huge variation. Me personally, I never got like enormous sex drive upregulation. I did get some, but nothing crazy. I've been up to as much as just north of 2000 milligrams per week.

But the sex drive component, especially if you have a lot of estrogen going on, qualitatively it can change, quantitatively it can change. Now, huge variation. Me personally, I never got like enormous sex drive upregulation. I did get some, but nothing crazy. I've been up to as much as just north of 2000 milligrams per week.

Currently, I'm only 250 milligrams per week, but my sex drive is more or less the same.

Currently, I'm only 250 milligrams per week, but my sex drive is more or less the same.

There are some reasons to believe that your androgen receptor density escalates up when exposed to more androgens and not down in some cases. And so that means the more gear you take, the more benefit you have, rather linearly. My experience, the experience of most people you talk to, it's, again, slow newsreel, same asymptotic curvilinear relationship.

There are some reasons to believe that your androgen receptor density escalates up when exposed to more androgens and not down in some cases. And so that means the more gear you take, the more benefit you have, rather linearly. My experience, the experience of most people you talk to, it's, again, slow newsreel, same asymptotic curvilinear relationship.

For me personally, and this is something I didn't discover until quite recently, I would say, unfortunately so, I get probably almost the same gains at 1000 milligrams that I do at 2000. Anything north for me of 1500 just drives me insane, mentally insane, and seems to not really affect my physique hardly at all. How much water retention do you get at these doses?

For me personally, and this is something I didn't discover until quite recently, I would say, unfortunately so, I get probably almost the same gains at 1000 milligrams that I do at 2000. Anything north for me of 1500 just drives me insane, mentally insane, and seems to not really affect my physique hardly at all. How much water retention do you get at these doses?

Considerable, although if you manage your estrogen well, it's not as much as you would think. Managing estrogen with aromatase inhibitors? Oh, yes, that's right. Sorry, I had a point there back then. Aromatase inhibitors in many cases are incredibly toxic drugs. And you generally want to avoid taking them if you can.

Considerable, although if you manage your estrogen well, it's not as much as you would think. Managing estrogen with aromatase inhibitors? Oh, yes, that's right. Sorry, I had a point there back then. Aromatase inhibitors in many cases are incredibly toxic drugs. And you generally want to avoid taking them if you can.

Sometimes you have to to get really dry for a contest, but that's only a few weeks out from the show.

Sometimes you have to to get really dry for a contest, but that's only a few weeks out from the show.

And so the modern wisdom, so to speak, with the evidence-based crowd, the safer use crowd, is to manage your estrogen with differential amounts of testosterone and non-estrogenically converting compounds like primobol and mastron versus taking just as much testosterone as you ever would, but taking an aromatase inhibitor on top of that.