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Nick Beeching

👤 Person
62 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

So you would test somebody who's infectious and test those around them.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

If you then had antibody tests as well, you could test those around them to see if they've already had the infection.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

So another way of, if I came into, you know, let's say a village and wanted to know who had had infection, then I would normally do an antibody testing and you'd see what proportion of the people at different ages had had infection from that test.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And you could ask them if they ever had any symptoms and work out how many

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

had the infection without having any symptoms.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And that's a common approach for many infections.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Well, as I said, looking for the virus, you want sensitivity, looking for the antibodies

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

in a sense, specificity is better.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

You don't want false positives.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

You want to be sure that a positive result is there.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

You want it to be pretty sensitive as well, but the specificity is more important.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

There are a lot of key workers, health care workers and others, people working in the community who are off work.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

They're self-isolating because they might have symptoms or they might be at risk or somebody in the house has a cough.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

It would be marvellous to have a blood test that said you've had this infection and we think it's safe for you to go back to work and look after other people.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

There is one caveat to that is that we don't yet know.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

If immunity is solid, in other words, if you've had the infection, we have a positive antibody test.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

We assume that you have quite good immunity, at least in the short term.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

But we won't know that, of course, until we follow people up for a few years.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

But even so, it would provide me with reassurance if I had a positive antibody test that at least I had some degree of immunity.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

I would return to work and I would still have to take appropriate precautions.