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Nick Norwitz

๐Ÿ‘ค Speaker
1350 total appearances

Appearances Over Time

Podcast Appearances

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

If you know, for the reasons I kind of just explained, does that make sense? So how high for how long you need to interpret the functional test score, the calcium score, or the coronary CT and geography score in the context of your prior exposure and whether anything has changed.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

If you know, for the reasons I kind of just explained, does that make sense? So how high for how long you need to interpret the functional test score, the calcium score, or the coronary CT and geography score in the context of your prior exposure and whether anything has changed.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

Well, I mean, it depends like what โ€“ I mean, like because โ€“ I mean, that's all in relative terms, right? So if you said, you know, something has 10 times the calories of a stick of celery, it's not that many calories. So, you know, what x-ray? Some modern x-rays don't have a lot of radiation, let's say like the dental x-ray. So I'm not sure.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

Well, I mean, it depends like what โ€“ I mean, like because โ€“ I mean, that's all in relative terms, right? So if you said, you know, something has 10 times the calories of a stick of celery, it's not that many calories. So, you know, what x-ray? Some modern x-rays don't have a lot of radiation, let's say like the dental x-ray. So I'm not sure.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

Well, I mean, it depends like what โ€“ I mean, like because โ€“ I mean, that's all in relative terms, right? So if you said, you know, something has 10 times the calories of a stick of celery, it's not that many calories. So, you know, what x-ray? Some modern x-rays don't have a lot of radiation, let's say like the dental x-ray. So I'm not sure.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I think if you quantified it in terms of โ€“ I'm not 100% sure about this, but I think if you quantified it in terms of โ€“ like background radiation, like exposure just from living in the free world, it's something like a few months. It's not negligible. I mean, I wouldn't get one every six months. I've gotten one and I thought it was, and I have friends that have gotten a few.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I think if you quantified it in terms of โ€“ I'm not 100% sure about this, but I think if you quantified it in terms of โ€“ like background radiation, like exposure just from living in the free world, it's something like a few months. It's not negligible. I mean, I wouldn't get one every six months. I've gotten one and I thought it was, and I have friends that have gotten a few.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I think if you quantified it in terms of โ€“ I'm not 100% sure about this, but I think if you quantified it in terms of โ€“ like background radiation, like exposure just from living in the free world, it's something like a few months. It's not negligible. I mean, I wouldn't get one every six months. I've gotten one and I thought it was, and I have friends that have gotten a few.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I don't think it's catastrophically high.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I don't think it's catastrophically high.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I don't think it's catastrophically high.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I love how you approached it. I think, you know, you got functional testing on yourself that informed your decision, and nevertheless, you went about doing a risk-benefit analysis that was right for you. You thought this medication had a low side effect profile, which I think generally it does, and also fit your physiology.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I love how you approached it. I think, you know, you got functional testing on yourself that informed your decision, and nevertheless, you went about doing a risk-benefit analysis that was right for you. You thought this medication had a low side effect profile, which I think generally it does, and also fit your physiology.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

I love how you approached it. I think, you know, you got functional testing on yourself that informed your decision, and nevertheless, you went about doing a risk-benefit analysis that was right for you. You thought this medication had a low side effect profile, which I think generally it does, and also fit your physiology.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

You know, the ezetimibe, as I know you know and your audience might know, it blocks cholesterol absorption at the level of the gut. So as a response, your liver increases the LDL receptors and pulls them out of the blood. More or less, it's acting locally at the intestines and then signaling to the liver.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

You know, the ezetimibe, as I know you know and your audience might know, it blocks cholesterol absorption at the level of the gut. So as a response, your liver increases the LDL receptors and pulls them out of the blood. More or less, it's acting locally at the intestines and then signaling to the liver.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

You know, the ezetimibe, as I know you know and your audience might know, it blocks cholesterol absorption at the level of the gut. So as a response, your liver increases the LDL receptors and pulls them out of the blood. More or less, it's acting locally at the intestines and then signaling to the liver.

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

So if the side effect profile is pretty low and the risk profile is pretty low and you're not having any symptomatic side effects, and all that's happening is a number on your lab report is going down that might reduce your risk or might not, but it might, then why not? In the risk-benefit analysis, the way I see you think through it is like, I am reassured by this functional test. Nevertheless...

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

So if the side effect profile is pretty low and the risk profile is pretty low and you're not having any symptomatic side effects, and all that's happening is a number on your lab report is going down that might reduce your risk or might not, but it might, then why not? In the risk-benefit analysis, the way I see you think through it is like, I am reassured by this functional test. Nevertheless...

Dhru Purohit Show
This Study Shocks Cardiologists: LDL and ApoB May Not Predict Heart Disease Risk in Healthy People with Dr. Nick Norwitz

So if the side effect profile is pretty low and the risk profile is pretty low and you're not having any symptomatic side effects, and all that's happening is a number on your lab report is going down that might reduce your risk or might not, but it might, then why not? In the risk-benefit analysis, the way I see you think through it is like, I am reassured by this functional test. Nevertheless...