Oprah Winfrey

You describe in Enough that the discovery of the GLP-1 medications is similar to the discovery of penicillin and insulin.

Why are these medications different than anything we've ever experienced before?

Yeah, yeah.

I think there's still a lot of confusion around how and why the GLP-1 medicines work.

This book goes into great detail that I know is going to help a lot of you on the journey be able to wrap your brains around this.

Can you explain it briefly, how it works?

Because you think it's working on your stomach.

It's not.

It's working on your brain.

The book is called Enough.

That's what the Enough meant to me.

Yeah.

We will be back in a moment with the legendary Serena Williams, who gets real about her struggle to lose weight after having children.

We're back on the Oprah podcast.

Dr. Anya and I are joined by Serena Williams, the greatest female tennis player in the history of the world, who opens up about the one opponent she could not defeat.

So this is what I know for sure, that some people, no matter what you do,

You can't lose the excess weight.

We've watched Serena Williams win championships after championships.

You all know she is the GOAT, the greatest of all times.

She is an elite world-class athlete working out every single day, eating healthy food.