Oprah Winfrey

And then you go back to – your body wants to keep going back.

For me, the weight is 211 pounds.

So when I pulled out the wagon of fat in 1988, I was – Wagon of fat on the Oprah Winfrey show, 67 pounds.

When I did that thing, I was 211 pounds.

When I did my first marathon, I was 211 pounds.

When I did – every time I – Before you lost the weight, you were 211 pounds.

Yeah.

Before I lost the weight to 211 pounds.

Then I gained the weight back and then went back to 211 pounds.

Did a marathon and then it went back to 200, you know, 220 pounds.

I mean, it's just my body is always trying to get between 211 and 220, 218.

So now with the help of this new revolutionary set of medications.

The set point in your body.

Everybody calls them weight loss drugs and you do lose weight, but really it is changing the set point in your brain so that your brain isn't trying to get to 211.

Your brain maybe is trying to get to 160 or 145 or whatever you're...

The set point is for you depending upon the dosage that you're taking.

Well, not only am I mirroring it with exercise, Rachel.

It actually has made a difference in the way I feel about exercising because now I can't believe it.

I'm going to the gym in the rain.

I'm going to the gym in the rain.