Paul Saladino, MD

So when you go to your doctor, and I want the people that are listening to think about this, and your doctor checks your cholesterol, how often does your doctor do any metric that approximates your insulin sensitivity? They're not really telling you about fasting insulin. I have to constantly talk to people and say, ask your doctor for a fasting insulin.

So when you go to your doctor, and I want the people that are listening to think about this, and your doctor checks your cholesterol, how often does your doctor do any metric that approximates your insulin sensitivity? They're not really telling you about fasting insulin. I have to constantly talk to people and say, ask your doctor for a fasting insulin.

It's a $30 test that your insurance should pay for, but maybe your insurance won't pay, but it's $30. For the amount of information it gives you, And most- Glucose, hemoglobin, A1C, insulin. All of those also, or ratios of triglycerides, right? But I think fasting insulin is such a good metric of insulin sensitivity and no one is getting it.

It's a $30 test that your insurance should pay for, but maybe your insurance won't pay, but it's $30. For the amount of information it gives you, And most- Glucose, hemoglobin, A1C, insulin. All of those also, or ratios of triglycerides, right? But I think fasting insulin is such a good metric of insulin sensitivity and no one is getting it.

It's a $30 test that your insurance should pay for, but maybe your insurance won't pay, but it's $30. For the amount of information it gives you, And most- Glucose, hemoglobin, A1C, insulin. All of those also, or ratios of triglycerides, right? But I think fasting insulin is such a good metric of insulin sensitivity and no one is getting it.

And you're interpreting lipids without any context of your insulin sensitivity. I think every lipid panel should be paired with insulin, fasting insulin, because your lipids matter in the context of your insulin sensitivity. And this goes back to Dave Feldman's research, which we will get to.

And you're interpreting lipids without any context of your insulin sensitivity. I think every lipid panel should be paired with insulin, fasting insulin, because your lipids matter in the context of your insulin sensitivity. And this goes back to Dave Feldman's research, which we will get to.

And you're interpreting lipids without any context of your insulin sensitivity. I think every lipid panel should be paired with insulin, fasting insulin, because your lipids matter in the context of your insulin sensitivity. And this goes back to Dave Feldman's research, which we will get to.

But I think that what's happening here for people, and this is where it gets really interesting, and we don't have randomized controlled trials here. So we're approximating mechanistic data, but it's really interesting to say that as we talked about earlier, when you eat polyunsaturated fats, they get stored in your body. We just are full of them.

But I think that what's happening here for people, and this is where it gets really interesting, and we don't have randomized controlled trials here. So we're approximating mechanistic data, but it's really interesting to say that as we talked about earlier, when you eat polyunsaturated fats, they get stored in your body. We just are full of them.

But I think that what's happening here for people, and this is where it gets really interesting, and we don't have randomized controlled trials here. So we're approximating mechanistic data, but it's really interesting to say that as we talked about earlier, when you eat polyunsaturated fats, they get stored in your body. We just are full of them.

And you mentioned a number earlier that it's important to bring up again, which is the fact that

And you mentioned a number earlier that it's important to bring up again, which is the fact that

And you mentioned a number earlier that it's important to bring up again, which is the fact that

Looking at kinetic studies of how we accumulate fatty acids, most people estimate that if you have been eating McDonald's and lots of seed oils your whole life, it takes you potentially four plus years if you stop today to fully recycle the membranes of all the cells in your body, the fatty acid depots, like the fat tissue probably being the least quick to recycle.

Looking at kinetic studies of how we accumulate fatty acids, most people estimate that if you have been eating McDonald's and lots of seed oils your whole life, it takes you potentially four plus years if you stop today to fully recycle the membranes of all the cells in your body, the fatty acid depots, like the fat tissue probably being the least quick to recycle.

Looking at kinetic studies of how we accumulate fatty acids, most people estimate that if you have been eating McDonald's and lots of seed oils your whole life, it takes you potentially four plus years if you stop today to fully recycle the membranes of all the cells in your body, the fatty acid depots, like the fat tissue probably being the least quick to recycle.

But it probably takes about four years to really fully change the composition of all the cell membranes and all the mitochondrial membranes. Wow. That's a big deal, right? There are potentially ways to speed that up that we can talk about, but they're pretty intense. Yeah, I'd like to talk about those.

But it probably takes about four years to really fully change the composition of all the cell membranes and all the mitochondrial membranes. Wow. That's a big deal, right? There are potentially ways to speed that up that we can talk about, but they're pretty intense. Yeah, I'd like to talk about those.

But it probably takes about four years to really fully change the composition of all the cell membranes and all the mitochondrial membranes. Wow. That's a big deal, right? There are potentially ways to speed that up that we can talk about, but they're pretty intense. Yeah, I'd like to talk about those.