Paul Saladino, MD

So potential energy in food, kinetic energy used to make a vital, fertile, happy, healthy human being, in between is our mitochondria. If you break the mitochondria, and you've spoken about this at length, if you break the mitochondria, you get stuck with potential energy. And what does that look like? That looks like fat humans. And so it's not just about calories. Fat, insulin-resistant humans.

It's not just about calories. It's about what are those calories doing to your cellular energy factories. If they are breaking your mitochondria, you are going to store more of those calories.

It's not just about calories. It's about what are those calories doing to your cellular energy factories. If they are breaking your mitochondria, you are going to store more of those calories.

It's not just about calories. It's about what are those calories doing to your cellular energy factories. If they are breaking your mitochondria, you are going to store more of those calories.

So when you look at a label on Doritos and it says 200 calories per serving, that is baloney because you can't actually make that Dorito into 200 calories of kinetic energy because there are ingredients in that Dorito, all sorts of ingredients, that are breaking your mitochondria. Hmm. And so when you stuff your mitochondrial membranes, right, there's two mitochondrial membranes.

So when you look at a label on Doritos and it says 200 calories per serving, that is baloney because you can't actually make that Dorito into 200 calories of kinetic energy because there are ingredients in that Dorito, all sorts of ingredients, that are breaking your mitochondria. Hmm. And so when you stuff your mitochondrial membranes, right, there's two mitochondrial membranes.

So when you look at a label on Doritos and it says 200 calories per serving, that is baloney because you can't actually make that Dorito into 200 calories of kinetic energy because there are ingredients in that Dorito, all sorts of ingredients, that are breaking your mitochondria. Hmm. And so when you stuff your mitochondrial membranes, right, there's two mitochondrial membranes.

The inner mitochondrial membrane is kind of the ground zero. Inside the mitochondria is where the Krebs cycle happens, in deep there. And as you are doing this electron transport chain, you are moving protons across those membranes to create a gradient.

The inner mitochondrial membrane is kind of the ground zero. Inside the mitochondria is where the Krebs cycle happens, in deep there. And as you are doing this electron transport chain, you are moving protons across those membranes to create a gradient.

The inner mitochondrial membrane is kind of the ground zero. Inside the mitochondria is where the Krebs cycle happens, in deep there. And as you are doing this electron transport chain, you are moving protons across those membranes to create a gradient.

And then the protons moving down the gradient through the little ATP motor, complex five of the mitochondrial electron transport chain, that's what makes ATP. But if those protons are leaking back across, you're not making ATP. And that happens when you stuff your mitochondria with polyunsaturated fatty acids. Wow. at an evolutionarily inappropriate level.

And then the protons moving down the gradient through the little ATP motor, complex five of the mitochondrial electron transport chain, that's what makes ATP. But if those protons are leaking back across, you're not making ATP. And that happens when you stuff your mitochondria with polyunsaturated fatty acids. Wow. at an evolutionarily inappropriate level.

And then the protons moving down the gradient through the little ATP motor, complex five of the mitochondrial electron transport chain, that's what makes ATP. But if those protons are leaking back across, you're not making ATP. And that happens when you stuff your mitochondria with polyunsaturated fatty acids. Wow. at an evolutionarily inappropriate level.

So there's lots of mechanisms by which stuffing your cells full of polyunsaturated fats creates a lot of problems for humans at this formation of energy level. And I think that's what's hard for people to wrap their head around because it's like, this is mechanistic research and we don't have a study in humans to prove that because who would fund it?

So there's lots of mechanisms by which stuffing your cells full of polyunsaturated fats creates a lot of problems for humans at this formation of energy level. And I think that's what's hard for people to wrap their head around because it's like, this is mechanistic research and we don't have a study in humans to prove that because who would fund it?

So there's lots of mechanisms by which stuffing your cells full of polyunsaturated fats creates a lot of problems for humans at this formation of energy level. And I think that's what's hard for people to wrap their head around because it's like, this is mechanistic research and we don't have a study in humans to prove that because who would fund it?

It's so tricky, but I think that it's pretty clear that We are doing something very wrong as humans today. It's not just that we are eating too many calories. We're eating slightly more calories. But, and I talk about this in the Fed Alive documentary, in the last 20 to 30 years in the United States, we have not increased calorie consumption at all. And obesity has gone from 30% to 42%.

It's so tricky, but I think that it's pretty clear that We are doing something very wrong as humans today. It's not just that we are eating too many calories. We're eating slightly more calories. But, and I talk about this in the Fed Alive documentary, in the last 20 to 30 years in the United States, we have not increased calorie consumption at all. And obesity has gone from 30% to 42%.

It's so tricky, but I think that it's pretty clear that We are doing something very wrong as humans today. It's not just that we are eating too many calories. We're eating slightly more calories. But, and I talk about this in the Fed Alive documentary, in the last 20 to 30 years in the United States, we have not increased calorie consumption at all. And obesity has gone from 30% to 42%.

We're not eating more calories. We're just getting fatter. What's going on? We're not converting the food energy to kinetic energy because we're breaking our mitochondria. And there are other things that I believe break mitochondria, but I think seed oils are a major factor. We've never had these in our diets at this level.