Paul Saladino, MD

You're not saying that there's corruption in our nutritional research. In the food industry, imagine that. Perhaps a little bit of corruption. We can talk about it. But what's so interesting when you think about this from the perspective of seed oils and the history is that we really have been, I believe, fed a lie regarding their benign nature or their health benefits.

And as you suggested, it kind of all... centers around this idea of cholesterol. So the only thing that seed oils might have going for them is that they lower ApoB. They lower your cholesterol, quote unquote. And the mainstream medical paradigm, which I was trained in, perhaps propagandized in- He's a medical doctor, by the way. He's an MD. Yeah. It's all about lowering cholesterol. Often-

And as you suggested, it kind of all... centers around this idea of cholesterol. So the only thing that seed oils might have going for them is that they lower ApoB. They lower your cholesterol, quote unquote. And the mainstream medical paradigm, which I was trained in, perhaps propagandized in- He's a medical doctor, by the way. He's an MD. Yeah. It's all about lowering cholesterol. Often-

And as you suggested, it kind of all... centers around this idea of cholesterol. So the only thing that seed oils might have going for them is that they lower ApoB. They lower your cholesterol, quote unquote. And the mainstream medical paradigm, which I was trained in, perhaps propagandized in- He's a medical doctor, by the way. He's an MD. Yeah. It's all about lowering cholesterol. Often-

in a myopic view, right? So if you are an MD, you are basically trained to lower ApoB and or LDL cholesterol, no matter what, without much attention to other metrics that may have more weight on your cardiovascular risk or that are simply more relevant, like oxidized LDL, LP little a, LPPLA2, which is lipoprotein associated phospholipase A2.

in a myopic view, right? So if you are an MD, you are basically trained to lower ApoB and or LDL cholesterol, no matter what, without much attention to other metrics that may have more weight on your cardiovascular risk or that are simply more relevant, like oxidized LDL, LP little a, LPPLA2, which is lipoprotein associated phospholipase A2.

in a myopic view, right? So if you are an MD, you are basically trained to lower ApoB and or LDL cholesterol, no matter what, without much attention to other metrics that may have more weight on your cardiovascular risk or that are simply more relevant, like oxidized LDL, LP little a, LPPLA2, which is lipoprotein associated phospholipase A2.

And this is where it starts to get interesting because I'll say this about seed oils. I think you could come to the conclusion that seed oils are benign for humans if You ignore all historical data, all evolutionary precedent. Humans have never had this in our diets.

And this is where it starts to get interesting because I'll say this about seed oils. I think you could come to the conclusion that seed oils are benign for humans if You ignore all historical data, all evolutionary precedent. Humans have never had this in our diets.

And this is where it starts to get interesting because I'll say this about seed oils. I think you could come to the conclusion that seed oils are benign for humans if You ignore all historical data, all evolutionary precedent. Humans have never had this in our diets.

You ignore all animal studies, which clearly show that seed oils increase rates of cancer, non-alcoholic steatohepatitis, which is liver injury. That's very bad in animals. They increase adiposity. They increase cardiovascular disease in animal models.

You ignore all animal studies, which clearly show that seed oils increase rates of cancer, non-alcoholic steatohepatitis, which is liver injury. That's very bad in animals. They increase adiposity. They increase cardiovascular disease in animal models.

You ignore all animal studies, which clearly show that seed oils increase rates of cancer, non-alcoholic steatohepatitis, which is liver injury. That's very bad in animals. They increase adiposity. They increase cardiovascular disease in animal models.

You have to ignore all mechanistic studies, which clearly show that linoleic acid, this 18-carbon omega-6 fatty acid, is very susceptible to oxidation in the biological systems.

You have to ignore all mechanistic studies, which clearly show that linoleic acid, this 18-carbon omega-6 fatty acid, is very susceptible to oxidation in the biological systems.

You have to ignore all mechanistic studies, which clearly show that linoleic acid, this 18-carbon omega-6 fatty acid, is very susceptible to oxidation in the biological systems.

And you also have to kind of cherry-pick the randomized controlled trials in humans and ignore the randomized controlled trials in humans that show that when you feed people seed oils versus olive oil or saturated fat, they have increased oxidized LDL, increased LP little a, and increased LP PLA. Increased LP little a? Uh-huh, increased LP little a, 7% to 10%.

And you also have to kind of cherry-pick the randomized controlled trials in humans and ignore the randomized controlled trials in humans that show that when you feed people seed oils versus olive oil or saturated fat, they have increased oxidized LDL, increased LP little a, and increased LP PLA. Increased LP little a? Uh-huh, increased LP little a, 7% to 10%.

And you also have to kind of cherry-pick the randomized controlled trials in humans and ignore the randomized controlled trials in humans that show that when you feed people seed oils versus olive oil or saturated fat, they have increased oxidized LDL, increased LP little a, and increased LP PLA. Increased LP little a? Uh-huh, increased LP little a, 7% to 10%.

That really helped. We can talk about LP little a because I want to share with you some data from my friend Dave Feldman about LP little a also. Really? Yeah. Yeah, we'll get to that.