Paul Saladino, MD

Yes.

There are so many markers of inflammation. And one of the things CRP does is bind to oxidized LDL, right? So CRP and oxidized LDL are intimately linked. And so to say that there's no inflammatory markers with seed oils is ludicrous. It's just closing your eyes and putting your hands in your ears and saying, la, la, la. I don't see any CRP.

There are so many markers of inflammation. And one of the things CRP does is bind to oxidized LDL, right? So CRP and oxidized LDL are intimately linked. And so to say that there's no inflammatory markers with seed oils is ludicrous. It's just closing your eyes and putting your hands in your ears and saying, la, la, la. I don't see any CRP.

There are so many markers of inflammation. And one of the things CRP does is bind to oxidized LDL, right? So CRP and oxidized LDL are intimately linked. And so to say that there's no inflammatory markers with seed oils is ludicrous. It's just closing your eyes and putting your hands in your ears and saying, la, la, la. I don't see any CRP.

Just because ESR doesn't go up, erythrocyte sedimentation rate with seed oils, there are so many markers of inflammation that increase when you fill the body with these oxidation-prone oils. And yet, the mainstream perspective, Harvard, Mayo, many... Apparently intelligent physicians in the community, longevity influencers are still holding fast to the claim that seed oils are benign for humans.

Just because ESR doesn't go up, erythrocyte sedimentation rate with seed oils, there are so many markers of inflammation that increase when you fill the body with these oxidation-prone oils. And yet, the mainstream perspective, Harvard, Mayo, many... Apparently intelligent physicians in the community, longevity influencers are still holding fast to the claim that seed oils are benign for humans.

Just because ESR doesn't go up, erythrocyte sedimentation rate with seed oils, there are so many markers of inflammation that increase when you fill the body with these oxidation-prone oils. And yet, the mainstream perspective, Harvard, Mayo, many... Apparently intelligent physicians in the community, longevity influencers are still holding fast to the claim that seed oils are benign for humans.

And so we just wanted it with Heart and Soil. I just wanted to make a documentary that got people talking about this.

And so we just wanted it with Heart and Soil. I just wanted to make a documentary that got people talking about this.

And so we just wanted it with Heart and Soil. I just wanted to make a documentary that got people talking about this.

a higher level asking questions about why we still think these are healthy, how anyone can even say that, because when you look at the highest level of evidence, the randomized controlled trials with seed oils, and I have a whole thread on X that I did months ago about this, and I just resurfaced the tweet this morning.

a higher level asking questions about why we still think these are healthy, how anyone can even say that, because when you look at the highest level of evidence, the randomized controlled trials with seed oils, and I have a whole thread on X that I did months ago about this, and I just resurfaced the tweet this morning.

a higher level asking questions about why we still think these are healthy, how anyone can even say that, because when you look at the highest level of evidence, the randomized controlled trials with seed oils, and I have a whole thread on X that I did months ago about this, and I just resurfaced the tweet this morning.

I broke down all 11 of the randomized controlled trials in humans with seed oils. Because that's the highest level of evidence, right? I went through it earlier in this podcast. We talked about evolutionarily inconsistent. We've never had seed oils in our diet. Mechanistic studies, very bad.

I broke down all 11 of the randomized controlled trials in humans with seed oils. Because that's the highest level of evidence, right? I went through it earlier in this podcast. We talked about evolutionarily inconsistent. We've never had seed oils in our diet. Mechanistic studies, very bad.

I broke down all 11 of the randomized controlled trials in humans with seed oils. Because that's the highest level of evidence, right? I went through it earlier in this podcast. We talked about evolutionarily inconsistent. We've never had seed oils in our diet. Mechanistic studies, very bad.

Historically, nuts, basically small amounts of nuts, but how many almonds can you eat? Almonds are a recent addition to the human diet. Sure, there are some hunter-gatherers that have mongongo nuts, the Khoisan, but most of us historically, throughout our evolution as humans, had very small amounts of polyunsaturated fats in our diets.

Historically, nuts, basically small amounts of nuts, but how many almonds can you eat? Almonds are a recent addition to the human diet. Sure, there are some hunter-gatherers that have mongongo nuts, the Khoisan, but most of us historically, throughout our evolution as humans, had very small amounts of polyunsaturated fats in our diets.

Historically, nuts, basically small amounts of nuts, but how many almonds can you eat? Almonds are a recent addition to the human diet. Sure, there are some hunter-gatherers that have mongongo nuts, the Khoisan, but most of us historically, throughout our evolution as humans, had very small amounts of polyunsaturated fats in our diets.

And if you look at hunter-gatherers or indigenous cultures, very small amounts, 1%, 2% of their calories from polyunsaturated fats. Versus 40%. Or 10% to 15% of our calories, and then it increases even from there for us. So average Americans today eat five tablespoons of some combination of seed oils. Five tablespoons. That's hundreds of calories.