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716 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So when you freeze sperm, it's about a 200-year-old process, regularly used for about 75. I forgot who the Italian scientist was who froze sperm in snow and then thawed it, and it was alive a couple hundred years later after Leeuwenhoek came up with a microscope. They found it was moving, and it was possible. So egg thawing is very new. Egg freezing and thawing is very new. This is very old.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So when you freeze sperm, it's about a 200-year-old process, regularly used for about 75. I forgot who the Italian scientist was who froze sperm in snow and then thawed it, and it was alive a couple hundred years later after Leeuwenhoek came up with a microscope. They found it was moving, and it was possible. So egg thawing is very new. Egg freezing and thawing is very new. This is very old.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So everyone is thinking about sperm now because eggs are being frozen left and right. but this is much older technology and the cell is much hardier than an egg. So it does a lot better typically. When you freeze it, it's the freezing process that kills sperm before icicles on the inside. And then while it's frozen, there's usually no issue.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So everyone is thinking about sperm now because eggs are being frozen left and right. but this is much older technology and the cell is much hardier than an egg. So it does a lot better typically. When you freeze it, it's the freezing process that kills sperm before icicles on the inside. And then while it's frozen, there's usually no issue.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And then there's another problem when you thaw it, rapid temperature shifts. So that's where the kill rate comes from. In a good sample, half of it should survive.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And then there's another problem when you thaw it, rapid temperature shifts. So that's where the kill rate comes from. In a good sample, half of it should survive.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So I usually say, depending on what technology you're going to use, but if your sperm counts normal... Three ejaculates is one kid's worth of sperm with insemination technology where you would thaw it and then turkey baste it.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So I usually say, depending on what technology you're going to use, but if your sperm counts normal... Three ejaculates is one kid's worth of sperm with insemination technology where you would thaw it and then turkey baste it.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So there's three levels, sex, no tech, high tech is IVF, and then the middle is IUI. That's the stuff that's turkey basting. It's relatively straightforward, relatively cheap. I see. Three kids for that, but plenty of sperm for IVF. So three ejaculates would be more than enough- If they're normal. For IVF. Yeah.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So there's three levels, sex, no tech, high tech is IVF, and then the middle is IUI. That's the stuff that's turkey basting. It's relatively straightforward, relatively cheap. I see. Three kids for that, but plenty of sperm for IVF. So three ejaculates would be more than enough- If they're normal. For IVF. Yeah.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So the population you're talking about, maybe cancer survivors, half of those will not be normal. They're really looking at IVF. Yep. So they don't need that many, but I'd say three is a good number, but it's an insurance policy, right? Yeah.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So the population you're talking about, maybe cancer survivors, half of those will not be normal. They're really looking at IVF. Yep. So they don't need that many, but I'd say three is a good number, but it's an insurance policy, right? Yeah.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Well, we started a podcast last year because of the blog of 15 years. And we're just doing timely topics and it's me and my associate Rob Clyde, who's a director in Hollywood. And we're going to be the anti-Bourdain in men's health.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Well, we started a podcast last year because of the blog of 15 years. And we're just doing timely topics and it's me and my associate Rob Clyde, who's a director in Hollywood. And we're going to be the anti-Bourdain in men's health.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

We're going to just take on the topics, testosterone, et cetera, penis myths, and just talk about stuff that everyone is asking questions about, but no one's talking about. And like you, data-driven answers.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

We're going to just take on the topics, testosterone, et cetera, penis myths, and just talk about stuff that everyone is asking questions about, but no one's talking about. And like you, data-driven answers.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Yes, I think it should be done. That's the first step. There's a lot going on now that the biomarker concept relates a lot to your views on medicine 3.0. The paper came out two days ago looking at longevity based on the semen analysis in Danish, in the Riggel Hospital in Copenhagen.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Yes, I think it should be done. That's the first step. There's a lot going on now that the biomarker concept relates a lot to your views on medicine 3.0. The paper came out two days ago looking at longevity based on the semen analysis in Danish, in the Riggel Hospital in Copenhagen.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

They looked at 74,000 men over 50 years and found that those guys with, say, normal semen quality lived three years longer, all causes, than men with low sperm counts when they were younger. This was a single payer system, so they have all the data on it. It's very much a landmark study.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

They looked at 74,000 men over 50 years and found that those guys with, say, normal semen quality lived three years longer, all causes, than men with low sperm counts when they were younger. This was a single payer system, so they have all the data on it. It's very much a landmark study.