Peter Attia, M.D.

Wow.

What an interesting phenotype.

They must have sky high estrogen given that all of their testosterone, male levels of testosterone are being converted to estradiol.

Do they develop with a male pattern of aggression or a female pattern of nurturing?

So outside of the sterility, I assume, of this individual, does she go on to be a completely normal woman?

So really not a pathologic condition outside of the sterility.

Wow.

Never even heard of this.

They don't have the aromatase capacity.

And they have the same libido?

And presumably they must have a little more difficulty putting on muscle mass.

To me, the most interesting outcome of the study was not, to my recollection, that the men with higher testosterone felt better.

It was that they actually put on more muscle mass as well.

Yeah, with the higher estrogen level.

So what do you think all of this teaches us about the role of testosterone replacement therapy in both men and women?

So let's go back to something you said some time ago.

So if we didn't muck around with nature, men would experience a pretty steady decline in testosterone from puberty on down.

Oh, okay.

We'll say more about that.

So that's the rut.