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Peter Attia, M.D.

๐Ÿ‘ค Speaker
589 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

In the case of the deer, all of the females go through esterase at the same time.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

So it's easier for the bucks to say for these nine months, I don't need testosterone because all of the does are infertile.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

And then bingo, now they're going through esterase.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

We're going to go through the rut and it's a party.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

Exactly.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

But with humans, I understand there's some literature that says the more women that are together, the more their cycle sinks.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

But that's got to be weak.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

It is.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

And by the way, women are ovulating every month.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

In other words, you're saying it's hard for us to blame fertility in the Western world on declining testosterone.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

Yeah, it could be the inflammation that arises from the metabolic dysfunction.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

Exactly.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

Exactly.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

Going back to kind of Western society, so we see this roughly 1% per year drop in testosterone.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

And so a guy in his 50s now has, hell, a guy in his 30s today has a lower testosterone than a guy in his 50s did 40 years ago.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

So a guy in his 50s today has pretty low testosterone.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

And

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

We certainly know that medically, it's a completely safe thing to replace.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

And we know that there are great outcomes with respect to bone health, with respect to frailty and many subjective findings.

The Peter Attia Drive
#374 - The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.

And we know that it's not increasing the risk of prostate cancer and heart disease and all the things we used to worry about outside of the edge case of hypertension, which can be managed.