Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Blog Pricing

Peter Attia

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
2609 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

If you're nutritionally at three or four millimole, I don't remember what my blood gas looked like,

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

Yeah.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

So do you think there's any meaningful application for a BHB monoester these days?

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

What is the application for that?

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

But I thought you said they didn't work well in epilepsy.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

Yeah, I'm talking about the original molecule from NIH that was a monoester of BHB.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

When you think about the advantages of lactate for alternative brain fuel and ketone as alternative brain fuel, I had George Brooks on the podcast a while ago and he talked about how you could probably rescue concussion patients if you administered lactate quickly following a concussion.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

Would you say the same is likely true for ketones?

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

Do you still use MCTs for anything?

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

And if you're taking the currently formulated ketone salt that you brought, you do not have to worry about the electrolyte load.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

So if you're consuming three of those a day, that would be three grams of additional electrolytes, which based on what you're also getting in your food, a lot of people would say, gosh, that's too many electrolytes.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

But you're not seeing the effect because of the lack of chloride.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

Yeah.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

And I think a lot of them are recommending, in my mind, erroneously, like two to three.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

Okay, I want to talk about two particular applications with ketogenic diets, one of which you've spoken about a little bit, the other one we've sort of talked about kind of indirectly.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

But let's say a word about what you think the future is for ketogenic diets and the treatment of cancer, and then separately for the treatment of dementia, specifically potentially Alzheimer's disease, but any form of dementia.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

You're at the entry of that zone.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

Let me ask a point-blank question, Dom.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

Glioblastoma carries with it a mortality rate of 100%.

The Peter Attia Drive
#375 - The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer's disease, brain injuries, and more | Dominic D'Agostino, Ph.D.

So it's been said that any patient who survives a glioblastoma has been misdiagnosed.