Peter Attia

Are those spread mostly between cancer, metabolic disease?

Anorexia is quite interesting.

What do you think is the hypothesis there?

Yes, it's the highest mortality rate.

And are they doing this with ketogenic diets, ketogenic diets plus supplements, just supplements?

If an individual says, look, I totally understand why a ketogenic diet might have efficacy for weight loss.

Could be multiple mechanisms that explain it.

But there are undoubtedly thousands of people listening to us who have no interest in weight loss.

They're at an appropriate weight.

They're happy with their weight.

But some of the things you've talked about might have piqued their curiosity with respect to performance.

Let's just start with cognitive performance.

Can you get all the same benefits of a person who slaves their way through what I used to do and you do and to varying degrees do?

You're on this very, very strict diet.

Can they get virtually all of those benefits through judicious use of ketone supplements?

Is it part of the mechanism that you just described earlier where, look, you ingest enough ketones, you're going to drive insulin enough, that's going to drive down glucose, which, by the way, would not be the most desirable way to lower glucose?

Define high in that setting.

And that occurs once you get above 2 or 3 millimole?

And presumably it's happening slowly enough that the redox reaction to balance your pH is happening.

You're going to blow off enough CO2, I assume, in that situation.