Peter Attia

And humans, we live 80 years.

We should probably be 40, according to the data.

By the way, we did live 40 years until modern medicine came along.

So maybe we were totally on the curve correctly until medicine 2.0 came around at the turn of the last century and basically over five generations doubled our lifespan.

Eric argues, I think this is a very interesting argument, rapamycin disproportionately works well in animals that are below the longevity quotient.

So that's why it works so reproducibly in mice.

But he argues it might not have any effect in humans because we've already captured so much of our genetic potential in terms of lifespan now that the idea that Rapa would give us an extra 15% of life, he feels is just kind of hard to imagine.

And again, it's a theoretical argument.

It's super interesting, but I'd never heard it in relation to the longevity quotient before.

And I thought it was very much worth pondering.

Yeah.

And then the question, of course, is, is there a way around that?

Is there a way where you could intermittently dose it?

You just take it once, you time it so that it's not in proximity to a bout of resistance training by a couple of days or something like that.

But yeah, there's a lot there.

Great expression I heard recently, which is mice usually lie.

Monkeys sometimes lie.

It's humans we care about.

That was just fantastic.

It was the human equivalent dose.