Peter Attia

And I think the same is true with mTOR.

Well, Eric Verdon made a very interesting comment on my podcast a while ago.

And so Eric is in the camp that he does not believe RAPPA will be geroprotective in humans.

And he talked about the longevity quotient.

So for listeners, the longevity quotient is a plot, a very famous plot that on the x-axis puts body size and on the y-axis puts lifespan.

And you just plot all the organisms on this thing.

And as a general rule, it rises up and to the right.

The larger an animal is, the longer it lives.

And it's a pretty straight line.

In fact, we should find a good example of it and link to it in the show notes.

But there are always animals that punch above and below their weight.

So there are animals that fall off that line either too high.

So these are animals that live much longer than you would expect based on their body size.

And there are animals that punch well below their body weight.

They live much shorter than they should based on their body weight.

Well, it turns out two interesting examples are mice and humans.

Mice live on average two years.

I forget the exact number.

They should be living close to four or five years, I think, based on the longevity quotient line.

So they are punching well below their weight.