Peter Attia

So there's also this challenge of trying to get folks to understand the difference between chronic and acute things.

Cortisol, great example.

So cortisol, vital hormone.

The appropriate rhythm of cortisol is essential for life.

If you took that away, you would actually be dead.

That's called Addison's disease.

But cortisol constantly being on would also be a problem.

That would be Cushing's disease.

So both extremes, bad.

It's do you know when you need it and what it's supposed to do?

And I think the same is true with mTOR.

Well, Eric Verdon made a very interesting comment on my podcast a while ago.

And so Eric is in the camp that he does not believe RAPPA will be geroprotective in humans.

And he talked about the longevity quotient.

So for listeners, the longevity quotient is a plot, a very famous plot that on the x-axis puts body size and on the y-axis puts lifespan.

And you just plot all the organisms on this thing.

And as a general rule, it rises up and to the right.

The larger an animal is, the longer it lives.

And it's a pretty straight line.

In fact, we should find a good example of it and link to it in the show notes.