Peter Attia

We might figure out a way to deliver IGF directly to muscles.

Like there might be a whole bunch of little things.

I don't know if you remember this.

I'm dating myself, but I don't know if you remember irisin.

Yeah.

Like, I mean, there are no shortage of these things.

Despite all the flack I'm taking, I'm going to just defend this one and continue.

And by the way, if new data emerge, I'm always happy to change my mind.

I've changed my mind about so many things.

It is absurd the number of things I've changed my mind on.

I've changed my mind on GLP-1s.

I've changed my mind on saunas.

I mean, I can count the list of things I've changed my mind on over the past 10 years.

If there are data that will make me change my mind, I will stand up here with a straight face and I will eat crow and I will tell you that I've changed my mind.

But I'm going to stand by my recommendation.

two grams per kilogram per day.

And my rationale, again, I explained it earlier in the podcast, but just to restate it, if you aim for two on the day you fall short, you'll still be at 1.6.

If you aim for 1.6 on the day you fall short, you'll be 1.2.

And that 1.2 won't be made up for on the next day because the downside is asymmetric compared to the upside.

So that's our recommendation clinically.