Peter Attia
π€ SpeakerAppearances Over Time
Podcast Appearances
I would chalk this up to one of those examples.
People also don't appreciate how short the half-life of IGF-1 is.
It's a staggeringly short half-life molecule.
Oh, really?
Oh, yeah, yeah.
It's insanely short half-life.
What's the half-life?
When administered systemically, it's on the order of minutes.
Yeah.
And by the way, administering IGF systemically is a lousy way to get it to the muscle.
You want to think of it almost as a paracrine thing where it has to be delivered into the muscle.
So look, all roads for me still point back to this idea that, and I know you would agree with me, so it's not going to be that controversial, but exercise is the most important drug.
I'm just not aware of a drug
in quotes, that is better than exercise.
And I know there's this enormous effort to figure out a way to put exercise into a pill.
I just can't imagine it'll ever happen.
It's not.
There might be several pills that come out of it.
We might figure out a way to make clotho.
We might figure out a way to make BDNF.