Menu
Sign In Search Podcasts Libraries Charts People & Topics Add Podcast API Blog Pricing

Professor Luke O'Neill

๐Ÿ‘ค Speaker
827 total appearances

Appearances Over Time

Podcast Appearances

Show Me the Science with Luke O'Neill
The Science of Gut Health

There are many, many different species there.

Show Me the Science with Luke O'Neill
The Science of Gut Health

making it very difficult.

Show Me the Science with Luke O'Neill
The Science of Gut Health

But this one, Barry Marshall famously found that Helicobacter in the gut was a huge risk factor for ulcers.

Show Me the Science with Luke O'Neill
The Science of Gut Health

Barry wins the Nobel Prize.

Show Me the Science with Luke O'Neill
The Science of Gut Health

If we kill those bacteria and antibiotics, ulcers go away.

Show Me the Science with Luke O'Neill
The Science of Gut Health

And this was a massive medical advance because before Barry discovered this, ulcers were thought to be caused by stress,

Show Me the Science with Luke O'Neill
The Science of Gut Health

The typical ulcer sufferer was a middle-aged man, not making his targets as a salesperson or whatever, drinking too many martinis and smoking too much.

Show Me the Science with Luke O'Neill
The Science of Gut Health

And hey, he gets an ulcer.

Show Me the Science with Luke O'Neill
The Science of Gut Health

But it turns out it's the bacteria that causes the ulcer.

Show Me the Science with Luke O'Neill
The Science of Gut Health

Now, the second thing is that it was also known that having Helicobacter increases the risk of gastric cancer.

Show Me the Science with Luke O'Neill
The Science of Gut Health

And that's why it's important to get rid of it.

Show Me the Science with Luke O'Neill
The Science of Gut Health

Now, why would it do that?

Show Me the Science with Luke O'Neill
The Science of Gut Health

Well, it causes inflammation, something I've often spoken about.

Show Me the Science with Luke O'Neill
The Science of Gut Health

And if you irritate the gut,

Show Me the Science with Luke O'Neill
The Science of Gut Health

with a bacteria that increases the risk of mutations in the cells in the gut that give rise to its humor developing.

Show Me the Science with Luke O'Neill
The Science of Gut Health

So the irritation, like an irritant, and we know many irritants cause cancer, so do bacteria, and in particular Helicobacter was linked to gastric cancer, very importantly.

Show Me the Science with Luke O'Neill
The Science of Gut Health

Another very important one, almost 20 odd years ago, Fusobacterium.

Show Me the Science with Luke O'Neill
The Science of Gut Health

Now you're going to be hearing lots of long names of the names of these species, because each bacteria species has a really complicated name.