Professor Luke O'Neill
speaker
1,535 appearances
7 recordings
2 series
first heard Apr 2026
last heard 3 Sep
Professor Luke O'Neill’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 7 in all, peaking in May 2026 with 3.
Appearances
There's a couple of breakthroughs recently.
There are two drugs actually, which somewhat slow it down, very small effect, but they do do something.
There's a big debate on that because the effect isn't huge and they're expensive.
And again, this week, actually a third drug was announced by Biogen.
And they claim it's slowing it down a little bit.
I'll come back to that in a minute when I come on to the mechanism of what's going on.
Now, what are these risk factors?
Well, when you put them all together and you observe them overall in the population, you will decrease your risk by 45%.
of Alzheimer's developing.
And that's across the entire population.
It's tricky these studies sometimes because they're population-based.
It doesn't mean that if an individual does them, they will have a 45% decrease risk.
Over the entire population, on average, there's a 45% decrease risk.
That's complicated, I know, but some don't respond to these modifications.
Some do.
It's a big mix.
So some people will follow them all and they'll still develop Alzheimer's, which tells us how complex this disease is.
But there's no doubt, though, from these guidelines who are issuing, if you do these things, there's a good chance you'll decrease the risk of developing Alzheimer's at least somewhat.
Now, what are they?
Well, it's the usual suspects.
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