Professor Luke O'Neill
speaker
1,535 appearances
7 recordings
2 series
first heard Apr 2026
last heard 3 Sep
Professor Luke O'Neill’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 7 in all, peaking in May 2026 with 3.
Appearances
And the spike sticks into a thing called beta-integrin or procarherin.
These are the things on the cells it's infecting.
And you'll see those things on the blood vessel cells, the endothelial cells.
You'll see them on macrophages, my favorite cell in my lab.
And it goes inside those cells by sticking the spike into the beta integrin.
And now it's inside and begins to grow and grow and grow.
And then you begin to see the immune response kicking in.
And that immune process can go out of control.
And as with most viral diseases, it's your own immune system that's gone into overdrive.
That's actually killing you and damaging your own tissues.
So the work on this is often very much focused on the immune side as much as on the virus side.
Now, one other thing to mention is the incidence, slight concern here, there may be increasing evidence for Hantavirus.
Two reasons, climate change.
Now, climate change, a lot of heat can mean more rats and mice.
Secondly, a lot of rainfall, the rats and mice are inclined to get into the trenches or into houses, so begin to infect people.
There's a slight concern now that if we see more rodents,
And especially rodents going indoors because of climate, we might see an increase in hantavirus being spread from the rodent into the humans.
And there's a slight concern, and that's being watched very, very closely at the moment as well, just to see.
And of course, when this thing happened on the cruise ship, the worry was something had changed.
But it hadn't changed.
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