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Professor Matthew Kiernan

๐Ÿ‘ค Speaker
877 total appearances

Appearances Over Time

Podcast Appearances

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

But I think what we've got to do is try and turn that around as a community and say, well, we're focusing on brain health.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

We want optimal brain function, and we want to get into it early, and we want to maintain it throughout the course of your life.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

So wouldn't it be great if people started going to their general practitioners at the age of 30 and had a brain health check?

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

to prevent dementia and neurodegeneration in the 60s, 70s, 80s, 90s.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

We don't know how long we're going to live for, but it's still going upwards.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

So I think that we can try and encourage a more healthy approach to brain health.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

Well, you've already articulated the main ones currently, but this is a rapidly evolving landscape.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

So, for instance, at Neuroscience Research Australia, we've formed a partnership with Roche Diagnostics Platform.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

And part of the reason for that is to get blood biomarkers as a Medicare item number so that people can go to their GP and have all of these.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

Get done for free.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

Yeah.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

And that's where it's going to be.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

That's going to be in the next five to 10 years.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

Right.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

There's been a huge study in the UK and they've taken blood and clinical examinations from 50,000 people.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

And they've gone back to the blood biomarkers and they've shown that if five particular proteins in the blood go up, about 10 years before Alzheimer's disease develops.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

And that's where we're going to be going.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

So we're going to be testing these in healthy individuals, and then we can start to treat against these blood biomarkers to try and maximize brain health.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

It's not here at the present, but there's a lot of work going on right now.

Straight Talk with Mark Bouris
Brain Expert: Why Dementia Is Australia's Number One Killer (Project 100)

At the moment, you can't, but that's exactly, so this sort of diagnostic pathway is to be doing amyloid and tau for Alzheimer's disease, TDP43 for motor neurone disease and frontotemporal dementia, alpha-synuclein for Lewy body dementia, Parkinson's disease.