Rhonda Patrick, Ph.D.

It forces them to also use just glucose without mitochondria.

Your muscle's like, dude, I need more mitochondria.

This isn't working, right?

So that's an adaptation that's happening and it makes sense.

And so I know a lot of people for, I've at least gotten a lot of questions from people talking about, but I thought zone two training was the best for mitochondria.

And

You know, it depends on what we're talking about here.

If we're talking about mitochondrial biogenesis, you know, great.

Zone 2 does increase mitochondrial biogenesis.

But, you know, if you start to go a little more vigorous, you actually can get a stronger stimulus.

And I know that's...

what we're talking about here, vigorous, includes zone two.

But I'm just saying, generally speaking, it just gets back to this whole idea, right?

The more intense the stimulus, the greater the adaptation to a degree.

Obviously, you don't want to go to the complete extreme where it's like, all you do is work out.

I'm not going to say that's all you do, but you definitely work out a lot.

Yeah, people can buy these lactate meters and it's a little finger prick test you can do.

And I've done it several times and it's kind of fun to do as well.

So I encourage people to try that out.

I think another sort of surrogate marker in my mind is also looking at oxidative stress markers.