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Rhonda Patrick

👤 Person
3409 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Are we ready to recommend more than the recommended daily allowance?

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And there's several of these out there.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

This is just one.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And essentially, if you have the time and the willingness to go into the scientific literature and actually read something for yourself or listen to The Drive or listen to my podcast and the actual experts talking about it, what you will hear or what you will learn is that a lot of the studies that were done to determine this phenomenon

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

RDA were flawed.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

They were called nitrogen balance studies.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And for many reasons, they're flawed.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I don't want to get into all the technical reasons, but for one, what they are doing is measuring the amount of nitrogen that is excreted in urine after you are metabolizing protein.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And some of the flaws that are, I would say, the most important here are that different types of foods that have protein in them have different nitrogen to protein ratios.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

They're collecting urine, in which the case is that it's an incomplete collection.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

I mean, like when you pee in one of those cups, you don't get all the urine.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

It's incomplete collection.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Yes, exactly.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

We lose nitrogen through other means.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And so essentially the signal to noise ratio is pretty low.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

Ultimately, what countless experts have now agreed upon is that the protein for the RDA has been underestimated because of those reasons.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

And there have been new studies that have been done.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

These have been like more stable isotope studies.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

The major isotope that's used is the L13 carbon labeling phenylalanine.

The Peter Attia Drive
#369 ‒ Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.

in which case these studies take a small cohort of people, give them a known amount of protein with that isotope tracer, and then that tracer is oxidized when it's metabolized, and that's measured through breath.