Rhonda Patrick

It's helped my mom with her tremors.

It's kind of amazing.

I've moved away from any sort of green powder supplements because I do think that they're just a high risk for heavy metals.

You can test this.

There's a variety of blood tests that you can do.

Add back in some green powders and you might see that your heavy metal burden goes up.

So that's kind of what I'm doing right now.

And then this is the last rapid fire question from Ted Ham.

And Ted asks, what are the best options for choline supplementation if one has

SNPs for poor phosphatidylcholine absorption or levels given the risk increase in TMAO levels.

Now, keep in mind, choline deficiency also leads to non-alcoholic fatty liver disease.

And so you want to be careful with that as well.

So the free choline salts...

are the forms that the microbes in the gut can actually ferment into TMAO.

Well, it actually ferments it into trimethylamine, and then that gets converted into TMAO, which is pro-atherogenic.

And that's what people are wanting to avoid.

So essentially, the goal would be to not have choline in this salt form.

You'd want choline in its already sort of pre-formed membrane-ready form.

part.

So in this case, you'd actually want to supplement with the phosphatidylcholine because the microbiome, the bacteria in the colon, wouldn't really be able to use that phosphatidylcholine, that colon that's already in this membrane, as a substrate to make the precursor for TMAO.