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Richard Scolyer

πŸ‘€ Speaker
408 total appearances

Appearances Over Time

Podcast Appearances

Conversations
Encore: The remarkable life of Professor Richard Scolyer

It may not be quite 0%, but we definitely will keep making progress and get very close to that.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

And indeed, I think ultimately we'll get to a stage where we'll get to zero deaths from all cancers, I hope.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

And if we talk about the progress, it was only 10 or so years, 15 years ago, that five-year survival rate for melanoma

Conversations
Encore: The remarkable life of Professor Richard Scolyer

for advanced stage when it was spread around your body was less than 5%.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

Now it's 57%.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

So that's a big jump.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

Yeah, with the treatments done by medical oncologists, there's a team of people that are working together.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

So what is immunotherapy and how does it work?

Conversations
Encore: The remarkable life of Professor Richard Scolyer

So compared to chemotherapy, where chemotherapy is basically poisoning all cells in your body, but hopefully having more of an effect on the cancer cells, there's side effects associated with it.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

But one of the types of cells that it's suppressing is the immune system.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

And we know, in fact, that many people are developing cancers that the body's immune system recognizes and kills off before anyone knows that it ever happened.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

But what happens is your cancer, some cancers can hide themselves from the immune system.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

They build up shields around themselves.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

And whilst they're still growing, the immune system can't get in to kill them off.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

And these new treatments, immunotherapy, basically break down those barriers to allow the immune system to recognize the cancer cells and to kill them off.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

And that's why it's so exciting.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

It's made incredible differences in melanoma and also now in many other cancers.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

It's used an improved outlook.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

But the one thing that's really been a game changer that's just come out in our melanoma work is what's called pre-surgery or neoadjuvant immunotherapy.

Conversations
Encore: The remarkable life of Professor Richard Scolyer

And that is if you give the immunotherapy when there's more tumour on board, for