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Robert Fried

πŸ‘€ Speaker
751 total appearances

Appearances Over Time

Podcast Appearances

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

But it was fatigue that we were most intrigued about because we know that's a mitochondrial thing.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

And we think that elevating NAD would have a benefit for all of these kinds of diseases.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

And they did this long COVID study, and it was a small study.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

They struggled to recruit people.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

They got only, I think, 58 people.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

And so to do a controlled study, a placebo study with only 58 people, that's not quite a hell of a lot of people.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

And when a study is that small, in order to achieve statistical significance, they have to have a very high level of improvement.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

And they completed the study, and the primary endpoint, which was comparing this small placebo team to this small NR team, they took two grams a day for 10 weeks, didn't show a difference.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

But when they took the placebo team, and they then started giving them NR for another 10 weeks,

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

So you had an additional 10 weeks with a much larger population.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

It did show a dramatic difference.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

So that's why we got excited about the results of that.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

And that was published, I think, just like a week or two ago.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

Wow.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

Very interesting.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

So it was then open label at that point, right?

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

Did the subjects know that they were getting active ingredient?

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

You mean after the first 10 weeks?

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

Yeah.

The Genius Life
541: Can a Pill Help You Live Longer? The Science Behind NAD and Longevity | Robert Fried

Yes.