Sal DiStefano
๐ค PersonAppearances Over Time
Podcast Appearances
You will run into this problem on a GLP-1, especially if you have a lot of weight to lose. You'll lose a significant percentage, but then you'll be stuck. And we run into this with people that we've coached where they had 80 pounds to lose. They lost, you know, 45 or 50 pounds. The last 30 pounds would not come off and they were eating very low calories. And like, what do I do now?
I can't eat any less. Where am I going to go down below a thousand calories? Now I'm feeling terrible. I have low energy. How do I lose this excess body fat? It's like your metabolism adapted. And so we don't want to lose muscle because that will make your metabolism slow down.
I can't eat any less. Where am I going to go down below a thousand calories? Now I'm feeling terrible. I have low energy. How do I lose this excess body fat? It's like your metabolism adapted. And so we don't want to lose muscle because that will make your metabolism slow down.
I can't eat any less. Where am I going to go down below a thousand calories? Now I'm feeling terrible. I have low energy. How do I lose this excess body fat? It's like your metabolism adapted. And so we don't want to lose muscle because that will make your metabolism slow down.
Yeah, but the big weight loss, that's what they hit.
Yeah, but the big weight loss, that's what they hit.
Yeah, but the big weight loss, that's what they hit.
Yeah, the way that GLP-1s work is they essentially tell your body you ate. They do increase the secretion of insulin. They do improve insulin sensitivity. This is all independent of weight loss. That's probably why there's a muscle-preserving effect because better insulin sensitivity is pro-muscle. And you see this in the stronger GLP-1s like Terzepatide.
Yeah, the way that GLP-1s work is they essentially tell your body you ate. They do increase the secretion of insulin. They do improve insulin sensitivity. This is all independent of weight loss. That's probably why there's a muscle-preserving effect because better insulin sensitivity is pro-muscle. And you see this in the stronger GLP-1s like Terzepatide.
Yeah, the way that GLP-1s work is they essentially tell your body you ate. They do increase the secretion of insulin. They do improve insulin sensitivity. This is all independent of weight loss. That's probably why there's a muscle-preserving effect because better insulin sensitivity is pro-muscle. And you see this in the stronger GLP-1s like Terzepatide.
I think Monjaro is the brand name of that one. And then now they have these even stronger ones that are coming out. So yeah, it doesn't cause muscle loss, but if you don't offset what'll happen when you simply eat less, you're not going to be in a great place. And my fear, because here's the deal with GLP-1s, these are culture-shifting compounds.
I think Monjaro is the brand name of that one. And then now they have these even stronger ones that are coming out. So yeah, it doesn't cause muscle loss, but if you don't offset what'll happen when you simply eat less, you're not going to be in a great place. And my fear, because here's the deal with GLP-1s, these are culture-shifting compounds.
I think Monjaro is the brand name of that one. And then now they have these even stronger ones that are coming out. So yeah, it doesn't cause muscle loss, but if you don't offset what'll happen when you simply eat less, you're not going to be in a great place. And my fear, because here's the deal with GLP-1s, these are culture-shifting compounds.
I mean, I think that you're going to see, you're probably going to see two-thirds of everyone uh, in a modern society like America is going to be on these. Cause that's how, that's how much overweight, uh, you know, and obesity, um, has now.
I mean, I think that you're going to see, you're probably going to see two-thirds of everyone uh, in a modern society like America is going to be on these. Cause that's how, that's how much overweight, uh, you know, and obesity, um, has now.
I mean, I think that you're going to see, you're probably going to see two-thirds of everyone uh, in a modern society like America is going to be on these. Cause that's how, that's how much overweight, uh, you know, and obesity, um, has now.
Um, and some people, uh, need less. Uh, but nonetheless, like if you do a GLP one, right. And there's a lot that goes into this. We're only going to really cover like how to prevent muscle loss, but there's a lot more that, uh, that we've talked about in previous episodes. If you do it right and you are the right person for this. I mean, I am, I think these are great.
Um, and some people, uh, need less. Uh, but nonetheless, like if you do a GLP one, right. And there's a lot that goes into this. We're only going to really cover like how to prevent muscle loss, but there's a lot more that, uh, that we've talked about in previous episodes. If you do it right and you are the right person for this. I mean, I am, I think these are great.
Um, and some people, uh, need less. Uh, but nonetheless, like if you do a GLP one, right. And there's a lot that goes into this. We're only going to really cover like how to prevent muscle loss, but there's a lot more that, uh, that we've talked about in previous episodes. If you do it right and you are the right person for this. I mean, I am, I think these are great.
I think they're great compounds. If used properly.