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Saranya Wyles, M.D., Ph.D.

๐Ÿ‘ค Speaker
416 total appearances

Appearances Over Time

Podcast Appearances

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

Lasers induce a controlled thermal injury.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

So they're like little micro columns of thermal heat injury that can then activate fibroblasts.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

They can then produce collagen.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

and elastin and healthy blood vessel formulation called androgenesis.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

So lasers are a dose-controlled way to stimulate these exact pathways that decline with age.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

And we recently did a study looking at patients before and after

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

an ablative laser and looking to see how they influence the senescent cells pathways.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

And what we show is that when you have a fractional CO2 or erbium laser, this can actually reduce your P16 senescent cells and restore a healthier fibroblast function.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

So they're actually helping to reset the skin function and kind of clear out the weeds of the senescent cells, if you will.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

So really, I think lasers are underestimated in this way to reset the skin and kind of create like healthier skin turnover.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

So there's a lot of different types of lasers.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

You could do a laser that has low downtime.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

So for some patients, downtime is really important to consider.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

They are not able to afford a week or two of taking time off and having a long recovery period.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

So yeah.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

If patients just have a shorter recovery period time, you can have them come in for a monthly laser, kind of a low energy type of laser that you could be doing once every three months or once a month where picogenesis is a laser that I commonly use in my practice.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

And we call it the lunchtime laser because it's super low downtime and people can come in and kind of get a

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

get a quick re-energy or reset of their skin and then kind of follow up over time.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

Or you can do more non-ablative lasers twice a year.

The mindbodygreen Podcast
632: The science of skin aging & how to slow it down | Saranya Wyles, M.D., Ph.D.

They do have about a three to five day downtime depending on the laser type.