Saranya Wyles, M.D., Ph.D.

Or you could do a more ablative laser, which depending on the depth of ablation could be done once every three years and you'd be good.

So a lot of potential.

Yeah.

So some lasers you're going to have, it's essentially creating a wound on your skin that is a very raw wound, especially with these ablative lasers.

So you could have swelling, redness that can last up to two to three days.

Some patients where it's an active wound, you can have oozing and a lot of debridement that you need to be actively doing so you can get crust formation on the skin.

A lot of times we talk about vinegar soaks that we're doing.

So patients are actively doing something on their skin multiple times a day to kind of taking care of an open wound, if you will.

So it takes about five to seven days with these truly ablative lasers, but you can also have

much lower downtime where maybe you're experiencing a little bit of light redness, which results in improvement by the end of the day.

It's non-ablative.

You can also do low procedures like microneedling.

There's also micro-focused ultrasound.

So different lasers or different ways to kind of stimulate or activate the fibroblasts.

Think about it like you just need to, it's almost like an injury-mediated collagen stimulation.

You need to create some sort of a trigger for these cells to wake up

clear their senescent cells and start to rebuild and rejuvenate.

So you're sort of rebooting that space.

So whether you're doing that by microneedling and waking them up or whether you're doing it by micro-focused ultrasound or a low-level laser, a non-ablative laser or a very aggressive ablative laser, it's all about kind of rebooting that system.

Exactly.