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Shana Kelley

👤 Person
179 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

that we could treat a tumor with them.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

So this is just kind of how the road of serendipity usually goes for us.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You know, unmet need, technology platform, always takes a while to find that kind of really compelling application, but we work and work and work till we

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

find something, and then we partner, we spin companies out.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

That company in particular that is taking the blood-borne tumor-reactive lymphocytes is taking that approach towards the clinic.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

And that's really my passion is developing these things and then trying to move them along so that they can have a positive impact on patients.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

And we're just kind of agnostic about that.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

All that really matters is the impact.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Yeah, that again, it was just another unsolved problem, something that we spotted that we thought was really interesting.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

And the problem that we're trying to tackle there is how do you get a molecule into a cell, but then into the mitochondria of the cell?

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

The mitochondria are doing all these really interesting things.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Those are the energy producers, obviously, but they have a lot of other signaling capabilities.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

There's DNA in mitochondria, which we don't completely understand what it does or doesn't do.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

So we just started developing chemical probes that could get there.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

And then we could ask a lot of questions about

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

on how all of the machinery and mitochondria works together.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

And it's been really fascinating.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

No startup there yet, but it's been a really interesting project.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Yeah, I think, you know, being interdisciplinary really helps.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You have to bring different things together.